Heterogeneous dopamine signals support distinct features of motivated actions: implications for learning and addiction
Explore this paper's citation graph
Summary
It is proposed that these spatiotemporally parallel dopaminergic signals are simultaneously available to the animal, but that these circuits are impaired following prolonged drug experience by disrupting the location and content of dopamine signals in afferent target regions.
- Type
- review
- Published
- 2018-08-16
- Cited by
- 6
- References
- 155
- Access
- Open access
- OpenAlex
- https://openalex.org/W2886115586
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:52016098
Keywords
Neuroscience, Addiction, Dopamine, Psychology, Context (archaeology)
References
- Mesolimbic dopamine dynamically tracks, and is causally linked to, discrete aspects of value-based decision making
- A theory of Pavlovian conditioning : Variations in the effectiveness of reinforcement and nonreinforcement
- Neural correlates of Pavlovian-to-instrumental transfer in the nucleus accumbens shell are selectively potentiated following cocaine self-administration
- Adolescent Alcohol Exposure Amplifies the Incentive Value of Reward-Predictive Cues Through Potentiation of Phasic Dopamine Signaling
- Methylphenidate and Cocaine Self-Administration Produce Distinct Dopamine Terminal Alterations
- Differential Dopamine Release Dynamics in the Nucleus Accumbens Core and Shell Reveal Complementary Signals for Error Prediction and Incentive Motivation
- Circuit Architecture of VTA Dopamine Neurons Revealed by Systematic Input–Output Mapping
- Distinct Subpopulations of Nucleus Accumbens Dynorphin Neurons Drive Aversion and Reward
- Catecholamines in the Bed Nucleus of the Stria Terminalis Reciprocally Respond to Reward and Aversion
- Unique properties of mesoprefrontal neurons within a dual mesocorticolimbic dopamine system.
- Dopamine Cells Respond to Predicted Events during Classical Conditioning: Evidence for Eligibility Traces in the Reward-Learning Network
- Differential dopamine release dynamics in the nucleus accumbens core and shell track distinct aspects of goal-directed behavior for sucrose
- Blockade of mesolimbic dopamine D3 receptors inhibits stress-induced reinstatement of cocaine-seeking in rats
- A cytoarchitectonic and chemoarchitectonic analysis of the dopamine cell groups in the substantia nigra, ventral tegmental area, and retrorubral field in the mouse
- Aversive Stimuli Differentially Modulate Real-Time Dopamine Transmission Dynamics within the Nucleus Accumbens Core and Shell
- Natural neural projection dynamics underlying social behavior
- Aversive behavior induced by optogenetic inactivation of ventral tegmental area dopamine neurons is mediated by dopamine D2 receptors in the nucleus accumbens
- Preferential activation of midbrain dopamine neurons by appetitive rather than aversive stimuli
- Dopamine reward circuitry: two projection systems from the ventral midbrain to the nucleus accumbens-olfactory tubercle complex.
- Dopamine Reward Prediction Error Responses Reflect Marginal Utility
Cited by
- Dopamine, endocannabinoids and their interaction in fear extinction and negative affect in PTSD.
- The Novel Analogue of Modafinil CE-158 Protects Social Memory against Interference and Triggers the Release of Dopamine in the Nucleus Accumbens of Mice
- Prelimbic cortex neural encoding dynamically tracks expected outcome value
- Voluntary alcohol consumption during distinct phases of adolescence differentially alters adult fear acquisition, extinction and renewal in male and female rats
- Voluntary alcohol consumption during distinct phases of adolescence differentially alters adult fear acquisition, extinction and renewal in male and female rats
- Investigating the effects of cocaine experience on dopaminergic and glutamatergic inputs to the nucleus accumbens using optical self-administration
Related papers
- A new mouse tool for studying dopaminergic neurons.
- Regulation of developing dopaminergic axonal arbor size in three‐dimensional reaggregate tissue culture
- Effects of compound Peibuganshen on cultured rat dopaminergic neurons injured by 1-methyl-4-phenylpyridinium
- Age-dependent changes in the mechanisms regulating dopamine uptake in the central nervous system.
- Effect of β-phenylethylamine on dopaminergic systems of the rat brain
- Dopamine re‐uptake inhibitor GBR‐12909 induction of aberrant behaviors in animal models of dopamine dysfunction
- Historical review: Molecular and cellular mechanisms of opiate and cocaine addiction.
- Common cellular and molecular mechanisms in obesity and drug addiction
- Evidence for Addiction-like Behavior in the Rat