Epac1 Restores Normal Insulin Signaling through a Reduction in Inflammatory Cytokines
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- Type
- article
- Published
- 2018-07-19
- Cited by
- 10
- References
- 33
- Access
- Open access
- OpenAlex
- https://openalex.org/W2883704580
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:52010303
Keywords
Insulin receptor, Insulin, Signal transduction, Tumor necrosis factor alpha, Biology
References
- β1-adrenergic receptor stimulation by agonist Compound 49b restores insulin receptor signal transduction in vivo
- Critical nodes in signalling pathways: insights into insulin action
- Regulation of the inflammatory response of vascular endothelial cells by EPAC1
- Tumor necrosis factor alpha-induced phosphorylation of insulin receptor substrate-1 (IRS-1). Possible mechanism for suppression of insulin-stimulated tyrosine phosphorylation of IRS-1.
- Interleukin-1β interferes with epidermal homeostasis through induction of insulin resistance: implications for psoriasis pathogenesis.
- Expression and regulation of adhesion molecules in cardiac cells by cytokines: response to acute hypoxia.
- Epac and the cardiovascular system.
- Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing
- TNFα and SOCS3 regulate IRS-1 to increase retinal endothelial cell apoptosis
- Pioglitazone Normalizes Insulin Signaling in the Diabetic Rat Retina through Reduction in Tumor Necrosis Factor α and Suppressor of Cytokine Signaling 3*
- SOCS-3 Inhibits Insulin Signaling and Is Up-regulated in Response to Tumor Necrosis Factor-α in the Adipose Tissue of Obese Mice*
- Differential Distribution of Epacs within the Adult Rat Retina
- Cyclic AMP inhibits JNK activation by CREB-mediated induction of c-FLIPL and MKP-1, thereby antagonizing UV-induced apoptosis
- Insulin/IGF-1 and TNF-alpha stimulate phosphorylation of IRS-1 at inhibitory Ser307 via distinct pathways.
- Long-term treatment with interleukin-1β induces insulin resistance in murine and human adipocytes
- A JNK-dependent pathway is required for TNFalpha-induced apoptosis.
- TNF-α mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations
- Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes
- Effects of Gevokizumab on Glycemia and Inflammatory Markers in Type 2 Diabetes
- Inhibition of Caspase-1/Interleukin-1β Signaling Prevents Degeneration of Retinal Capillaries in Diabetes and Galactosemia
Cited by
- HMGB1 inhibits insulin signaling through TLR4 and RAGE in human retinal endothelial cells
- Epac1 and Glycyrrhizin Both Inhibit HMGB1 Levels to Reduce Diabetes-Induced Neuronal and Vascular Damage in the Mouse Retina
- Epac1 inhibits PKR to reduce NLRP3 inflammasome proteins in retinal endothelial cells
- Condemned or Not to Die? Gene Polymorphisms Associated With Cell Death in Pemphigus Foliaceus
- Epac: A Promising Therapeutic Target for Vascular Diseases: A Review
- Association of helicobacter pylori infection with lipid metabolism and 10-year cardiovascular risk in diabetes mellitus: A cross-sectional study
- Role of exchange proteins directly activated by cAMP signaling in vascular remodeling.
- Selective EPAC1 Activators Enhance Endothelial Function in Models of Vascular Inflammation.
- Selective Epac1 Activators Enhance Endothelial Function in Models of Vascular Inflammation
- Erratum to “Epac1 Restores Normal Insulin Signaling through a Reduction in Inflammatory Cytokines”
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