Bacteroidetes Neurotoxins and Inflammatory Neurodegeneration
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Summary
For the first time, these results indicate that specific GI tract microbiome-derived neurotoxins have a strong pathogenic role in eliciting alterations in NF-kB-miRNA-directed gene expression that drives the AD process.
- Type
- review
- Published
- 2018-04-10
- Cited by
- 118
- References
- 85
- OpenAlex
- https://openalex.org/W2796859943
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4713602
Keywords
Neurodegeneration, Biology, microRNA, Innate immune system, Cell biology
References
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Cited by
- Role of microRNA (miRNA) and Viroids in Lethal Diseases of Plants and Animals. Potential Contribution to Human Neurodegenerative Disorders
- microRNA diagnostic panel for Alzheimer's disease and epigenetic trade-off between neurodegeneration and cancer.
- Aluminum in neurological disease – a 36 year multicenter study
- The Role of Ceramide and Sphingosine-1-Phosphate in Alzheimer’s Disease and Other Neurodegenerative Disorders
- miR‐98 acts as an inhibitor in chronic constriction injury‐induced neuropathic pain via downregulation of high‐mobility group AT‐hook 2
- Aluminum in Neurological and Neurodegenerative Disease
- microRNA-34a (miRNA-34a) Mediated Down-Regulation of the Post-synaptic Cytoskeletal Element SHANK3 in Sporadic Alzheimer's Disease (AD)
- Lipopolysaccharide-Induced Neuroinflammation as a Bridge to Understand Neurodegeneration
- Down-Regulation of Essential Synaptic Components by GI-Tract Microbiome-Derived Lipopolysaccharide (LPS) in LPS-Treated Human Neuronal-Glial (HNG) Cells in Primary Culture: Relevance to Alzheimer’s Disease (AD)
- A potential species of next-generation probiotics? The dark and light sides of Bacteroides fragilis in health.
- Lipopolysaccharide-stimulated, NF-kB-, miRNA-146a- and miRNA-155-mediated molecular-genetic communication between the human gastrointestinal tract microbiome and the brain.
- Aluminum-induced generation of lipopolysaccharide (LPS) from the human gastrointestinal (GI)-tract microbiome-resident Bacteroides fragilis
- Gut Microbiota: From the Forgotten Organ to a Potential Key Player in the Pathology of Alzheimer’s Disease
- MiR-495 targeting dvl-2 represses the inflammatory response of ankylosing spondylitis.
- Modified Huang-Lian-Jie-Du Decoction Ameliorates Aβ Synaptotoxicity in a Murine Model of Alzheimer's Disease
- Calorie restriction slows age-related microbiota changes in an Alzheimer’s disease model in female mice
- Facilitation of Gastrointestinal (GI) Tract Microbiome-Derived Lipopolysaccharide (LPS) Entry Into Human Neurons by Amyloid Beta-42 (Aβ42) Peptide
- The role of gut microbiota, butyrate and proton pump inhibitors in amyotrophic lateral sclerosis: a systematic review
- Gut Microbiota Imbalance is Related to Sporadic Colorectal Neoplasms. A Pilot Study
- Subacute Neuropsychiatric Syndrome in Girls With SHANK3 Mutations Responds to Immunomodulation
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