Progress and challenges towards targeted delivery of cancer therapeutics
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Summary
The principles behind targeted delivery approaches are reviewed to determine potential reasons for their limited clinical translation and success and criteria and considerations that must be taken into account for the development of novel actively targeted NCs are proposed.
- Type
- review
- Published
- 2018-04-12
- Cited by
- 1,839
- References
- 102
- Access
- Open access
- OpenAlex
- https://openalex.org/W2796781998
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4782883
Keywords
Nanocarriers, Targeted therapy, Clinical trial, Medicine, Cancer
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- Therapeutic Potency of Nanoformulations of siRNAs and shRNAs in Animal Models of Cancers
- Icariin Activates Autophagy via Down-Regulation of the NF-κB Signaling-Mediated Apoptosis in Chondrocytes
- Microneedles Integrated with ZnO Quantum-Dot-Capped Mesoporous Bioactive Glasses for Glucose-Mediated Insulin Delivery.
- Dipeptide-modified nanoparticles to facilitate oral docetaxel delivery: new insights into PepT1-mediated targeting strategy
- Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial
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- A Novel Top-Down Synthesis of Ultrathin Two-Dimensional Boron Nanosheets for Multi-modal Imaging-Guided Cancer Therapy
- Two-Dimensional Antimonene-Based Photonic Nanomedicine for Cancer Theranostics
- Dual-Responsive Core Crosslinking Glycopolymer-Drug Conjugates Nanoparticles for Precise Hepatocarcinoma Therapy
- Cancer hallmarks and malignancy features: Gateway for improved targeted drug delivery.
- Rational Design of Nanoparticles with Deep Tumor Penetration for Effective Treatment of Tumor Metastasis
- Biologically Targeted Magnetic Hyperthermia: Potential and Limitations
- Controlled Drug Delivery by Polylactide Stereocomplex Micelle for Cervical Cancer Chemotherapy
- Nanomedicines for Pediatric Cancers.
- Photoluminescence immunoassay based on grapefruit peel-extracted carbon quantum dots encapsulated into silica nanospheres for p53 protein
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