Molecular Architecture of the Mouse Nervous System
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Summary
RNA sequencing of half a million single cells is used to create a detailed census of cell types in the mouse nervous system and lays a solid foundation for understanding the molecular architecture of the mammalian nervous system, and enables genetic manipulation of specific cell types.
- Type
- preprint
- Published
- 2018-04-06
- Cited by
- 2,372
- References
- 65
- Access
- Open access
- OpenAlex
- https://openalex.org/W2795478605
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:51940430
Keywords
Nervous system, Biology, Neuroscience, Cell type, Central nervous system
References
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- Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1.
- Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
- Isolation of high-purity myenteric plexus from adult human and mouse gastrointestinal tract
- Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase.
- Local leaders in random networks.
- Neural crest origin of olfactory ensheathing glia
- Fundamentals of planarian regeneration.
- Immunohistochemical analysis of neuron types in the mouse small intestine
- Intersectional Illumination of Neural Circuit Function
- Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing
- Foxj1 transcription factors are master regulators of the motile ciliogenic program
- Mind matters: Placebo enhances reward learning in Parkinson’s disease
- Nervenkitt: Notes on the history of the concept of neuroglia
- Massively parallel single cell RNA-Seq for marker-free decomposition of tissues into cell types
- Why glycine transporters have different stoichiometries
Cited by
- Regulation of the apical extension morphogenesis tunes the mechanosensory response of microvilliated neurons
- Connect-seq to superimpose molecular on anatomical neural circuit maps
- The human and mouse enteric nervous system at single cell resolution
- RNA velocity of single cells
- Spatial reconstruction of single enterocytes uncovers broad zonation along the intestinal villus axis
- High-throughput mapping of long-range neuronal projection using in situ sequencing
- Sparse reduced-rank regression for exploratory visualization of multimodal data sets
- Childhood Cerebellar Tumors Mirror Conserved Fetal Transcriptional Programs
- Single cell multi-omics: an engine for new quantitative models of gene regulation
- Cell-specific histone modification maps link schizophrenia risk to the neuronal epigenome
- Sequencing Diversity One Cell at a Time.
- A single cell transcriptomic analysis of human neocortical development
- Antagonistic Effect of a Cytoplasmic Domain on the Basal Activity of Polymodal Potassium Channels
- Single-cell transcriptional dynamics and origins of neuronal diversity in the developing mouse neocortex
- Revealing the Critical Regulators of Cell Identity in the Mouse Cell Atlas
- The accessible chromatin landscape of the hippocampus at single-cell resolution
- Assessing Transcriptome Quality in Patch-Seq Datasets
- A spatial atlas of inhibitory cell types in mouse hippocampus
- Comparative Analysis of cul5 and rbx2 Expression in the Developing and Adult Murine Brain and Their Essentiality During Mouse Embryogenesis
- Lineages and molecular heterogeneity in the developing nervous system
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