Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results
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Summary
Specific standards designed to maintain rigor while also promoting communication are proposed for the interpretation of linkage results in genetic studies under way for many complex traits.
- Type
- article
- Published
- 1995-11-01
- Cited by
- 5,455
- References
- 44
- OpenAlex
- https://openalex.org/W1976741643
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6953087
Keywords
Linkage (software), Biology, Interpretation (philosophy), Genetic linkage, Computational biology
References
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- Asymptotic properties of affected-sib-pair linkage analysis.
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- The transmission/disequilibrium test: history, subdivision, and admixture.
- Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27.
- Construction of a genetic linkage map in man using restriction fragment length polymorphisms.
- A potential vulnerability locus for schizophrenia on chromosome 6p24–22: evidence for genetic heterogeneity
- Report of the Committee on Unassigned Syntenic Groups and Theoretical Considerations.
- On the lod score method in linkage analysis
- A multisample bootstrap approach to the estimation of maximized-over-models lod score distributions.
- Re-evaluation of the linkage relationship between chromosome 11p loci and the gene for bipolar affective disorder in the Old Order Amish
- Genetic analysis of type 1 diabetes using whole genome approaches.
- Diminished support for linkage between manic depressive illness and X–chromosome markers in three Israeli pedigrees
- Stereotactic management of midline brain lesions.
- Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31–q33
- Mapping disease genes: family-based association studies.
- Genetic linkage between X-chromosome markers and bipolar affective illness
- Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus
Cited by
- Genetic susceptibility to dental implant failure: a critical review.
- Using discordant sib pairs to map loci for qualitative traits with high sibling recurrence risk.
- A Quantitative Genetic Analysis of Slow-Wave Sleep and Rapid-Eye Movement Sleep in CXB Recombinant Inbred Mice
- Étude d'association entre certains gènes candidats et l'asthme dans une cohorte familiale originaire du Saguenay-Lac-Saint-Jean : réflexion sur l'analyse d'interaction gène-gène
- A region on bovine chromosome 15 influences beef longissimus tenderness in steers.
- Molecular genetic analysis of the role of GABAergic systems in the behavioral and cellular actions of alcohol
- Genetically complex cardiovascular traits. Origins, problems, and potential solutions.
- Non-insulin-dependent diabetes mellitus--a collision between thrifty genes and an affluent society.
- Suggestive evidence for a schizophrenia susceptibility locus on chromosome 6q and a confirmation in an independent series of pedigrees.
- Molecular linkage studies of bipolar disorder
- Modeling the phenotype in parametric linkage analysis of bipolar disorder
- Efficient localization of mutations by interval haplotype analysis
- Are there anxious genes?
- Mapping of genetic modulators of natural resistance to infection with Salmonella typhimurium in wild-derived mice.
- Evidence that genetic susceptibility to Mycobacterium tuberculosis in a Brazilian population is under oligogenic control: linkage study of the candidate genes NRAMP1 and TNFA.
- Further investigation of a chromosome 15 locus in schizophrenia: analysis of affected sibpairs from the NIMH Genetics Initiative.
- Genetic analysis of susceptibility to dextran sulfate sodium-induced colitis in mice.
- Guidelines for the study of familial dilated cardiomyopathies. Collaborative Research Group of the European Human and Capital Mobility Project on Familial Dilated Cardiomyopathy.
- Infection and disease in human schistosomiasis mansoni are under distinct major gene control.
- A genome-wide search for genes predisposing to familial psoriasis by using a stratification approach
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