Modulation of the gut microbiota by metformin improves metabolic profiles in aged obese mice
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Summary
It is suggested that modulation of the gut microbiota by metformin results in metabolic improvements in aged mice, and that these effects are associated with inflammatory immune responses.
- Type
- article
- Published
- 2018-02-13
- Cited by
- 175
- References
- 55
- Access
- Open access
- OpenAlex
- https://openalex.org/W2768863811
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205955342
Keywords
Akkermansia muciniphila, Metformin, Akkermansia, Gut flora, Biology
References
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- Interactions between Bifidobacterium and Bacteroides Species in Cofermentations Are Affected by Carbon Sources, Including Exopolysaccharides Produced by Bifidobacteria
Cited by
- Effect of metformin on sepsis-associated acute lung injury and gut microbiota in aged rats with sepsis
- Le transfert de microbiote fécal : quel potentiel thérapeutique dans le traitement des maladies métaboliques ?
- Metformin: old friend, new ways of action–implication of the gut microbiome?
- Metformin and Autoimmunity: A “New Deal” of an Old Drug
- Metformin Alters Gut Microbiota of Healthy Mice: Implication for Its Potential Role in Gut Microbiota Homeostasis
- Metformin: Focus on Melanoma
- Lactobacillus acidophilus DDS-1 Modulates the Gut Microbiota and Improves Metabolic Profiles in Aging Mice
- Enduring neurobehavioural effects induced by early-life microbiota-gut-brain axis alterations
- RapidAIM: a culture- and metaproteomics-based Rapid Assay of Individual Microbiome responses to drugs
- Effect of Metformin on Antipsychotic-Induced Metabolic Dysfunction: The Potential Role of Gut-Brain Axis
- Gut Microbiota Shapes the Efficiency of Cancer Therapy
- An in vitro model maintaining taxon-specific functional activities of the gut microbiome
- The role of gut microbiota in obesity, diabetes mellitus, and effect of metformin: new insights into old diseases.
- Metformin and Dipeptidase Peptidyl-4 Inhibitor Differentially Modulate the Intestinal Microbiota and Plasma Metabolome of Metabolically Dysfunctional Mice.
- Lactobacillus acidophilus DDS-1 Modulates Intestinal-Specific Microbiota, Short-Chain Fatty Acid and Immunological Profiles in Aging Mice
- Metformin as an archetype immuno-metabolic adjuvant for cancer immunotherapy
- Changes in Gut Microbiome after Bariatric Surgery Versus Medical Weight Loss in a Pilot Randomized Trial
- Fecal Microbiota Transplantation: a Future Therapeutic Option for Obesity/Diabetes?
- Alterations in Gut Microbiota by Statin Therapy and Possible Intermediate Effects on Hyperglycemia and Hyperlipidemia
- Metformin as Anti-Aging Therapy: Is It for Everyone?
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