Comprehensive functional genomics using Caenorhabditis elegans as a model organism
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Summary
This work first used cell-type specific markers and preexisting mutants to investigate how genotype-phenotype causal relationships are regulated and with the aid of transgenic methods, it analyzed various biological processes in C. elegans.
- Type
- article
- Published
- 2017-10-11
- Cited by
- 15
- References
- 83
- Access
- Open access
- OpenAlex
- https://openalex.org/W2761746945
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21370540
Keywords
Model organism, Caenorhabditis elegans, Biology, Organism, Functional genomics
References
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- Genetic regulation of mec‐3 gene expression implicated in the specification of the mechanosensory neuron cell types in Caenorhabditis elegans
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- Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells.
- C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells through phospholipid scramblase SCRM-1
- The Secreted Metalloprotease ADAMTS20 Is Required for Melanoblast Survival
- Caspase-Dependent Conversion of Dicer Ribonuclease into a Death-Promoting Deoxyribonuclease
Cited by
- Gap junctions in the C. elegans nervous system regulate ageing and lifespan
- Carbonic Anhydrase VI : Functional characterization in mouse and zebrafish model organisms
- Anthelmintic drug discovery: target identification, screening methods and the role of open science
- Efficient collection of a large number of mutations by mutagenesis of DNA damage response defective animals
- A Flexible Network of Lipid Droplet Associated Proteins Support Embryonic Integrity of C. elegans
- The permanently chaperone-active small heat shock protein Hsp17 from Caenorhabditis elegans exhibits topological separation of its N-terminal regions
- IPPK-1 and IP6 contribute to ventral nerve cord assembly in C. elegans
- A Comparative Analysis on Detecting Physiological Age of Caenorhabditis Elegans Using Deep Learning Techniques
- Nuclear hormone receptor regulation of PAL-1/Caudal mediates ventral nerve cord assembly in C. elegans
- Systematic optimization of Caenorhabditis elegans cryopreservation
- Systematic optimization of Caenorhabditis elegans cryopreservation
- Early life starvation and Hedgehog-related signaling activate innate immunity downstream of daf-18/PTEN and lin-35/Rb causing developmental pathology in adult C. elegans
- A flexible network of lipid droplet associated proteins support embryonic integrity of C. elegans
- Systematic Optimization of Caenorhabditis Elegans Cryopreservation
- Tiny Models to Answer Big Questions: The Worm and the Yeast as Tools in Human Genetics Research
- Glycobiology of Caenorhabditis elegans
- The effects of endophytic fungal metabolites from Conyza blinii on antioxidant capacity and healthspan in Caenorhabditis elegans.
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