Effect of Population Size and Mutation Rate on the Evolution of RNA Sequences on an Adaptive Landscape Determined by RNA Folding
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Summary
The observations show that mutation rate and population size can interact in complex ways to influence the adaptive dynamics of a population on a biophysically motivated fitness landscape.
- Type
- article
- Published
- 2017-09-05
- Cited by
- 11
- References
- 86
- Access
- Open access
- OpenAlex
- https://openalex.org/W2756193737
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11106901
Keywords
Fitness landscape, Population, Mutation rate, Population size, Effective population size
References
- The igraph software package for complex network research
- The Princeton Guide to Evolution
- Effects of genotype on rates of substitution during experimental evolution
- Principles of population genetics
- The fate of competing beneficial mutations in an asexual population
- EVOLUTIONARY ADVANTAGE OF SMALL POPULATIONS ON COMPLEX FITNESS LANDSCAPES
- Niche expansion in bacteria: can infectious gene exchange affect the rate of evolution?
- On the probability of fixation of mutant genes in a population.
- Clonal interference in large populations
- Long-Term Experimental Evolution in Escherichia coli. I. Adaptation and Divergence During 2,000 Generations
- Estimation of census and effective population sizes: the increasing usefulness of DNA-based approaches
- Predictability of evolution depends nonmonotonically on population size
- Stochastic Tunnels in Evolutionary Dynamics
- From sequences to shapes and back: a case study in RNA secondary structures
- Prediction of RNA secondary structures: from theory to models and real molecules
- Limits to adaptation in asexual populations
- Competing islands limit the rate of adaptation in structured populations.
- The Rate of Fitness-Valley Crossing in Sexual Populations
- Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations.
- Mutation-selection networks of cancer initiation: tumor suppressor genes and chromosomal instability.
Cited by
- Empirical Investigations OF RNA Fitness Landscapes: Harnessing the Power of High-Throughput Sequencing and Evolutionary Simulations
- Probing pathways of adaptation with continuous evolution
- Why is cyclic dominance so rare?
- Adaptation of turnip mosaic potyvirus to a specific niche reduces its genetic and environmental robustness
- Distinct evolutionary trajectories in asexual populations through an interplay of their size, resource availability and mutation rates
- Intra-Population Competition during Adaptation to Increased Temperature in an RNA Bacteriophage
- Endosymbiotic ratchet accelerates divergence after organelle origin
- Unravelling the factors of evolutionary repeatability: insights and perspectives on predictability in evolutionary biology
- Suffering makes you weaker: Limited evolutionary adaptation in competitively inferior populations.
- Synthetic niches enable co-culture bioprocessing but are prone to mutational escape
- The Thermodynamic Considerations of Evolution; the Role of Entropy in Biological Complexity
- The Thermodynamic Considerations of Evolution; the Role of Entropy in Biological Complexity
- The Thermodynamic Considerations of Biological Evolution; the Role of Entropy
- Dispersal Enhances Abiotic Adaptation in Populations Under Interspecific Competition Compared to Isolation
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