Minimap2: pairwise alignment for nucleotide sequences
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Summary
Minimap2 is a general-purpose alignment program to map DNA or long mRNA sequences against a large reference database and is 3-4 times as fast as mainstream short-read mappers at comparable accuracy, and is ≥30 times faster than long-read genomic or cDNA mapper at higher accuracy, surpassing most aligners specialized in one type of alignment.
- Type
- article
- Published
- 2017-08-04
- Cited by
- 13,516
- References
- 40
- Access
- Open access
- OpenAlex
- https://openalex.org/W2750666499
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3964249
Keywords
Pairwise comparison, Nucleotide, Computational biology, Biology, Genetics
References
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- Benchmarking spliced alignment programs including Spaln2, an extended version of Spaln that incorporates additional species-specific features
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- Putative host-derived insertions in the genome of circulating SARS-CoV-2 variants
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- Genetic depletion does not prevent rapid evolution in island‐introduced lizards
- The genomes of the aquarium sponges Tethya wilhelma and Tethya minuta (Porifera: Demospongiae)
- Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours
- Chiron: translating nanopore raw signal directly into nucleotide sequence using deep learning
- MetaCompass: Reference-guided Assembly of Metagenomes
- Differential and defective expression of Koala Retrovirus reveal complexity of host and virus evolution
- Real-time analysis of nanopore-based metagenomic sequencing from orthopaedic device infection
- Hercules: a profile HMM-based hybrid error correction algorithm for long reads
- A synthetic-diploid benchmark for accurate variant calling evaluation
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- Culture-independent analysis of liver abscess using nanopore sequencing
- Firefly genomes illuminate parallel origins of bioluminescence in beetles
- Introducing difference recurrence relations for faster semi-global alignment of long sequences
- Rapid Multiplex Small DNA Sequencing on the MinION Nanopore Sequencing Platform
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