Sense and antisense Oligodeoxynucleotides to Glun1 Nmdar are Cognitive Enhancers (Nootropics) and protective agents in normal and ischemic (Anoxic) conditions- In vitro study
Explore this paper's citation graph
Summary
Treatment of slices with aODNs and sODNs contributed to the preservation of synaptic activity which has been blocked in the control untreated slices, and directed upand down regulation of NMDAR might be useful in the readjustment of brain activity by the controlling balance of excitation/inhibition.
- Type
- article
- Published
- 2017-07-07
- Cited by
- 0
- References
- 58
- Access
- Open access
- OpenAlex
- https://openalex.org/W2743160536
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26958689
Keywords
Anoxic waters, In vitro, Cognition, Sense (electronics), Enhancer
References
- The essential role of AMPA receptor GluR2 subunit RNA editing in the normal and diseased brain
- Exposure of Neurons to Excitotoxic Levels of Glutamate Induces Cleavage of ADAR2 and Loss of GluR2 Editing
- Rapid and Transient Learning-Associated Increase in NMDA NR1 Subunit in the Rat Hippocampus
- Regulation of synaptic signalling by postsynaptic, non‐glutamate receptor ion channels
- Brain edema induced by in vitro ischemia: causal factors and neuroprotection
- NMDA Receptor Subunits in the Adult Rat Hippocampus Undergo Similar Changes after 5 Minutes in an Open Field and after LTP Induction
- NMDA receptor function: subunit composition versus spatial distribution
- The NMDA receptor as a target for cognitive enhancement
- Hsp70 promotes synaptic transmission in brain slices damaged by contact with blood clot.
- Distribution and quantification of NMDA R1 mRNA and protein in the piglet brainstem and effects of intermittent hypercapnic hypoxia (IHH).
- NMDA receptor‐deficient mice display sexual dimorphism in the onset and severity of behavioural abnormalities
- An Antisense Oligonucleotide to the N-Methyl-d-aspartate (NMDA) Subunit NMDAR1 Attenuates NMDA-Induced Nociception, Hyperalgesia, and Morphine Tolerance
- Antinociceptive effects after intrathecal administration of phosphodiester-, 2'-O-allyl-, and C-5-propyne-modified antisense oligodeoxynucleotides targeting the NMDAR1 subunit in mouse.
- PDZ Protein Interactions Underlying NMDA Receptor-Mediated Excitotoxicity and Neuroprotection by PSD-95 Inhibitors
- NMDA receptor subunits: function and pharmacology.
- Role of NMDA Receptor Subtypes in Governing the Direction of Hippocampal Synaptic Plasticity
- Experience-dependent changes in NMDA receptor composition at mature central synapses.
- Surface trafficking of NMDA receptors: gathering from a partner to another.
- Glutamate Receptor Ion Channels: Structure, Regulation, and Function
- Preweaning Sensorimotor Deficits and Adolescent Hypersociability in Grin1 Knockdown Mice
Cited by
No citing papers recorded for this paper.
Related papers
- Adaptation of the methanogenic granules to denitrification in anaerobic-anoxic USSB reactor.
- Effect of oxygen on the stability and inducibility of the biodegradative capability of benzoate.
- Device of anoxic chamber system and repair of potentially lethal damage of anoxic cells in vitro.
- Effect of Hydraulic Loading on Anoxic-Aerobic BAF in Domestic Sewage
- Optimisation of anaerobic/anoxic/oxic process to improve performance and reduce operating costs
- Corrosion behavior of a powdered simulated nuclear waste glass under anoxic condition
- Degradation of dissolved organic matter in oxic and anoxic lake water
- Biodegradation of Phosphorous in a Laboratory-scale Sequential Batch Reactor under Anoxic–Aerobic Conditions
- Optimization of A2O Process by Changing Anoxic Tank Volume Based on GPS-X Simulation