The interplay between iron and oxygen homeostasis with a particular focus on the heart.
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Summary
This review summarizes current knowledge on the interplay between oxygen and iron homeostasis and describes recent insights gained into this interaction in the context of the heart, including the recognition that the hepcidin/ferroportin axis plays a vital role in the regulation of intracellular ironHomeostasis as well as regulating systemic iron availability.
- Type
- review
- Published
- 2017-10-01
- Cited by
- 26
- References
- 65
- Access
- Open access
- OpenAlex
- https://openalex.org/W2743009057
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21555063
Keywords
Hepcidin, Homeostasis, Ferroportin, Hypoxia (environmental), Iron homeostasis
References
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- Lethal cardiomyopathy in mice lacking transferrin receptor in the heart
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- Tissue oxygenation and capacity to deliver O2 do the two go together?
- FERROKINETICS IN MAN
- Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase
- The role of iron regulatory proteins in mammalian iron homeostasis and disease
- Coordinate regulation of glycolysis by hypoxia in mammalian cells
- IDENTIFICATION OF ERYTHROFERRONE AS AN ERYTHROID REGULATOR OF IRON METABOLISM
- Iron-regulatory proteins limit hypoxia-inducible factor-2α expression in iron deficiency
Cited by
- EFFECTS OF MODEST IRON LOADING ON IRON INDICES IN HEALTHY INDIVIDUALS.
- Cardiomyocyte hepcidin: From intracellular iron homeostasis to physiological function.
- Influence of mitochondrial and systemic iron levels in heart failure pathology
- Leishmania amazonensis ferric iron reductase (LFR1) is a bifunctional enzyme: Unveiling a NADPH oxidase activity.
- Cardiomyopathy in Thalassemia: Quick Review from Cellular Aspects to Diagnosis and Current Treatments.
- Intravenous iron and chronic obstructive pulmonary disease: a randomised controlled trial
- The Molecular Mechanisms of Iron Metabolism and Its Role in Cardiac Dysfunction and Cardioprotection
- Effect of PM10 on pulmonary immune response and fetus development.
- Reproducibility of liver R2* quantification for liver iron quantification from cardiac R2* acquisitions
- Lactate production can function to increase human epithelial cell iron concentration
- Iron supplementation inhibits hypoxia-induced mitochondrial damage and protects zebrafish liver cells from death
- Cardiac Hamp mRNA Is Predominantly Expressed in the Right Atrium and Does Not Respond to Iron
- Chiral Polymer Micelles Alleviate Adriamycin Cardiotoxicity via Iron Chelation and Ferroptosis Inhibition
- Essential and non-essential elements in tuna and billfish around the world: Distribution patterns and influencing factors.
- Computational evaluation of heart failure and continuous flow left ventricular assist device support in anaemia
- Iron deficiency and supplementation in heart failure
- Determination of calcium, iron, and selenium in human serum by isotope dilution analysis using nitrogen microwave inductively coupled atmospheric pressure plasma mass spectrometry (MICAP-MS)
- Iron and cardiovascular health: A review
- Minerals and Human Health: From Deficiency to Toxicity
- Dietary iron interacts with diet composition to modulate the endocannabinoidome and the gut microbiome in mice
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