Roles of the hepcidin–ferroportin axis and iron in cancer
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Summary
Parts of the hepcidin–ferroportin axis and iron regulation are discussed, as well as the inherent connections between them in cancer, to consider the possibility in theory of novel targets for further individualized therapy.
- Type
- review
- Published
- 2014-03-01
- Cited by
- 43
- References
- 120
- OpenAlex
- https://openalex.org/W2010681884
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:23561091
Keywords
Hepcidin, Ferroportin, Iron homeostasis, Cancer, Homeostasis
References
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Cited by
- Hepcidin - A novel biomarker with changing trends
- Iron, inflammation and invasion of cancer cells
- Methyl Sulfone Blocked Multiple Hypoxia- and Non-Hypoxia-Induced Metastatic Targets in Breast Cancer Cells and Melanoma Cells
- Hepcidin quantification: methods and utility in diagnosis.
- In Situ OH Generation from O2 − and H2O2 Plays a Critical Role in Plasma-Induced Cell Death
- The Interface Between Iron Metabolism and Gene-Based Iron Contrast for MRI
- Serum hepcidin level and disease course of acute leukemia in children
- Preoperative mean corpuscular hemoglobin affecting long-term outcomes of hepatectomized patients with hepatocellular carcinoma.
- Iron and cancer: recent insights
- Is there any role of intravenous iron for the treatment of anemia in cancer?
- On the self-dependent effect of metal nanoparticles on malignant tumors
- Elevated expression of ZNF217 promotes prostate cancer growth by restraining ferroportin-conducted iron egress
- Hepcidin and DNA promoter methylation in hepatocellular carcinoma
- Iron therapy as treatment of anemia: A potentially detrimental and hazardous strategy in colorectal cancer patients.
- Low ferroportin expression in AML is correlated with good risk cytogenetics, improved outcomes and increased sensitivity to chemotherapy.
- The effect of red blood cell transfusion on plasma hepcidin and growth differentiation factor 15 in gastric cancer patients: a prospective study.
- Iron and hepcidin mediate human colorectal cancer cell growth.
- Iron Metabolism in Cancer Progression
- The prognostic roles of red blood cell-associated indicators in patients with resectable gastric cancers
- Iron Dysregulation in Human Cancer: Altered Metabolism, Biomarkers for Diagnosis, Prognosis, Monitoring and Rationale for Therapy
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