Sex-specific gene expression and life span regulation
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Summary
Maternal transmission of mitochondria to offspring may lead to greater control over mitochondrial functions in females, including greater life span and a larger response to diet in females, in both flies and mice.
- Type
- review
- Published
- 2017-08-02
- Cited by
- 113
- References
- 83
- Access
- Open access
- OpenAlex
- https://openalex.org/W2741213675
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3720780
Keywords
Biology, Proteotoxicity, Offspring, Population, Mitochondrion
References
- Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster
- Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans
- Drosophila melanogaster Hsp22: a mitochondrial small heat shock protein influencing the aging process
- Influence of non-steroidal anti-inflammatory drugs on Drosophila melanogaster longevity
- Unusual maintenance of X chromosome inactivation predisposes female lymphocytes for increased expression from the inactive X
- Evidence for compensatory upregulation of expressed X-linked genes in mammals, Caenorhabditis elegans and Drosophila melanogaster
- Comparative and meta‐analytic insights into life extension via dietary restriction
- Sex Differences in Longevity and in Responses to Anti-Aging Interventions: A Mini-Review
- Distinct shifts in microbiota composition during Drosophila aging impair intestinal function and drive mortality
- A Mild Impairment of Mitochondrial Electron Transport Has Sex-Specific Effects on Lifespan and Aging in Mice
- Rapamycin-Mediated Lifespan Increase in Mice is Dose and Sex-Dependent and Appears Metabolically Distinct from Dietary Restriction
- Increased internal and external bacterial load during Drosophila aging without life-span trade-off.
- Heat shock proteins and Drosophila aging
- Stress and stem cells
- General theory of mortality and aging.
- Mitochondrial maintenance failure in aging and role of sexual dimorphism
- The sirtuin SIRT6 regulates lifespan in male mice
- Genetic Analysis of dTSPO, an Outer Mitochondrial Membrane Protein, Reveals Its Functions in Apoptosis, Longevity, and Aβ42-induced Neurodegeneration
- Validated analysis of mortality rates demonstrates distinct genetic mechanisms that influence lifespan.
- Complex-I-ty in aging
Cited by
- Sex differences in the response to dietary restriction in rodents
- Sexual Dimorphism in Drug Metabolism and Pharmacokinetics.
- SEXUAL DIMORPHISM IN OXIDANT-INDUCED ADAPTIVE HOMEOSTASIS IN MULTIPLE WILD-TYPE D. MELANOGASTER STRAINS
- Experimental Gerontology
- MECHANISMS IN ENDOCRINOLOGY: Lessons from growth hormone receptor gene-disrupted mice: are there benefits of endocrine defects?
- Sex differences in transcriptomic profiles in aged kidney cells of renin lineage
- Sex Differences in Early Embryogenesis: Inter‐Chromosomal Regulation Sets the Stage for Sex‐Biased Gene Networks
- Sex differences and the neurobiology of affective disorders
- Superior Intrinsic Mitochondrial Respiration in Women Than in Men
- Neuron‐specific overexpression of core clock genes improves stress‐resistance and extends lifespan of Drosophila melanogaster
- Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease
- Sex-specific stress tolerance, proteolysis, and lifespan in the invertebrate Tigriopus californicus
- Growth signaling and longevity in mouse models
- Sex-specific differences in the intracellular proteome of human endothelial cells from dizygotic twins.
- The sex- and duration-dependent effects of intermittent fasting on lifespan and reproduction of spider mite Tetranychus urticae
- Parasitic worm product ES-62 promotes healthspan and lifespan in a model of obesity induced ageing
- Disordered Expression of shaggy, the Drosophila Gene Encoding a Serine-Threonine Protein Kinase GSK3, Affects the Lifespan in a Transcript-, Stage-, and Tissue-Specific Manner
- Boolean gene regulatory network model of centromere function in Saccharomyces cerevisiae
- Drosophila flies in the face of aging.
- Effects of oxidative stress on sex-specific gene expression in the copepod Tigriopus californicus revealed by single individual RNA-seq
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