A compendium of ERK targets

Keywords

Compendium, MAPK/ERK pathway, Computational biology, Computer science, Biology

References

• Signal transduction through MAP kinase cascades.Robin Zondervan — 1998
• Phosphoproteomic Analysis of Cell-Based Resistance to BRAF Inhibitor Therapy in MelanomaRobert Parker, Laura J. Vella, Dylan Xavier — 2015
• Biological sequence motif discovery using motif-x.Michael F. Chou, Daniel Schwartz — 2011
• Large-scale Discovery of ERK2 Substrates Identifies ERK-Mediated Transcriptional Regulation by ETV3Scott M. Carlson, Candace R. Chouinard, Adam Labadorf — 2011
• Modeling Signaling Networks to Advance New Cancer Therapies.Julio Sáez-Rodríguez, Aidan MacNamara, Simon J. Cook — 2015
• The dynamic control of signal transduction networks in cancer cellsWalter Kölch, Melinda Halász, Marina Granovskaya — 2015
• PhosphOrtholog: a web-based tool for cross-species mapping of orthologous protein post-translational modificationsRima Chaudhuri, Arash Sadrieh, Nolan J. Hoffman — 2015
• Identification of Extracellular Signal-regulated Kinase 1 (ERK1) Direct Substrates using Stable Isotope Labeled Kinase Assay-Linked Phosphoproteomics*Liang Xue, Pengcheng Wang, Pianpian Cao — 2014
• Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transportHidetaka Kosako, Nozomi Yamaguchi, Chizuru Aranami — 2009
• Time-resolved Mass Spectrometry of Tyrosine Phosphorylation Sites in the Epidermal Growth Factor Receptor Signaling Network Reveals Dynamic Modules*SYi Zhang, Alejandro Wolf‐Yadlin, Phillip Ross — 2005
• ERK1/2 MAP kinases in cell survival and apoptosisZhimin Lu, Shuichan Xu — 2006
• An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data setsDaniel Schwartz, Steven P. Gygi — 2005
• The nucleoporin Nup98 associates with the intranuclear filamentous protein network of TPRBeatriz M. A. Fontoura, Samuel Dales, Günter Blobel — 2001
• ProteoConnections: A bioinformatics platform to facilitate proteome and phosphoproteome analysesMathieu Courcelles, Sébastien Lemieux, Laure Voisin — 2011
• Quantitative proteomics and phosphoproteomics reveal novel insights into complexity and dynamics of the EGFR signaling networkSandra Morandell, Taras Stasyk, Sergej Skvortsov — 2008
• A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signalingBlagoy Blagoev, Irina Kratchmarova, Shao‐En Ong — 2003
• Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancerPatrick J. Roberts, Channing J. Der — 2007
• Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b.Chung-I Chang, Bing-e Xu, Radha Akella — 2002
• The extracellular signal-regulated kinase: Multiple substrates regulate diverse cellular functionsSeunghee Yoon, Rony Seger — 2006
• The MAPK signaling cascadeRony Seger, E G Krebs — 1995

Cited by

• ERK Activation and Its Role in Pancreatic Acinar Cell FunctionJohn A. Williams and Bryan J. Holtz — 2017
• ERK1/2 inhibitors: New weapons to inhibit the RAS‐regulated RAF‐MEK1/2‐ERK1/2 pathwayAndrew M. Kidger, James Sipthorp, Simon J. Cook — 2018
• Extracellular Regulated Kinases: Signaling from Ras to ERK Substrates to Control Biological OutcomesScott T. Eblen — 2018
• Structural fingerprints, interactions, and signaling networks of RAS family proteins beyond RAS isoformsSaeideh Nakhaei‐Rad, Fereshteh Haghighi, Parivash Nouri — 2018
• Specificity of Phosphorylation Responses to Mitogen Activated Protein (MAP) Kinase Pathway Inhibitors in Melanoma Cells*Joel Basken, Scott A. Stuart, Andrew J. Kavran — 2017
• When more is less: Dual phosphorylation protects signaling off-state against overexpressionFranziska Witzel, Nils Blüthgen — 2018
• Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3Wei Xie, Yangliang Ye, Ying Feng — 2018
• KRAS Suppression-Induced Degradation of MYC is Antagonized by a MEK5-ERK5 Compensatory MechanismAngelina V. Vaseva, Devon R. Blake, Thomas S.K. Gilbert — 2018
• From oncogenic mutation to dynamic codeWalter Kölch, Christina Kiel — 2018
• The Nuclear Translocation of Mitogen-Activated Protein Kinases: Molecular Mechanisms and Use as Novel Therapeutic TargetKaren Flores, Suresh Singh Yadav, Arieh A. Katz — 2018
• Development and Characterization of Novel RAF Dimer Inhibitors to Target BRAFV600e Inhibitor ResistanceM. Grasso — 2018
• Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastropheBastian Gastl, Kathleen Klotz‐Noack, Bertram Klinger — 2020
• Targeting ERK1/2 protein-serine/threonine kinases in human cancers.Robert Roskoski — 2019
• Cholecystokinin (CCK) Regulation of Pancreatic Acinar Cells: Physiological Actions and Signal Transduction MechanismsJohn A. Williams — 2019
• Nuclear ERK: Mechanism of Translocation, Substrates, and Role in CancerGalia Maik-Rachline, Avital Hacohen-Lev-Ran, Rony Seger — 2019
• Glutathione transferase Omega 1‐1 (GSTO1‐1) modulates Akt and MEK1/2 signaling in human neuroblastoma cell SH‐SY5YChonticha Saisawang, Jantana Wongsantichon, Robert Robinson — 2019
• Targeting the ERK Signaling Pathway in MelanomaPaola Savoia, Paolo Fava, Filippo Casoni — 2019
• Biological Rationale for Targeting MEK/ERK Pathways in Anti-Cancer Therapy and to Potentiate Tumour Responses to RadiationFrancesco Marampon, Carmela Ciccarelli, Bianca M. Zani — 2019
• Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 PathwayPatrycja Szybowska, Michał Kostas, Jørgen Wesche — 2019
• Rewiring of RSK-PDZ interactome by linear motif phosphorylationGergő Gógl, Beáta Biri‐Kovács, Fabien Durbesson — 2019

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