Mechanisms of Disease: Psoriasis.
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Summary
Anti-TNF strategies have three variants: a humanized chimeric anti–TNF- α monoclonal antibody, a fully human monocolonal anti-T NF- α antibody, and a human p75 TNF-receptor Fc fusion protein.
- Type
- review
- Published
- 2009-07-30
- Cited by
- 1,991
- References
- 94
- Access
- Open access
- OpenAlex
- https://openalex.org/W2561759163
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:203791161
Keywords
Medicine, Psoriasis, Dermatology, Family medicine
References
- Interleukin-12 p40 gene (IL12B) 3'-untranslated region polymorphism is associated with susceptibility to atopic dermatitis and psoriasis vulgaris.
- From classical mouse models of psoriasis to a spontaneous xenograft model featuring use of AGR mice.
- Evidence for an antigen-specific cellular immune response in skin lesions of patients with psoriasis vulgaris.
- Identification of Cellular Pathways of “Type 1,” Th17 T Cells, and TNF- and Inducible Nitric Oxide Synthase-Producing Dendritic Cells in Autoimmune Inflammation through Pharmacogenomic Study of Cyclosporine A in Psoriasis1
- Clinical and genetic registries in psoriatic disease.
- Dysfunctional Blood and Target Tissue CD4+CD25high Regulatory T Cells in Psoriasis: Mechanism Underlying Unrestrained Pathogenic Effector T Cell Proliferation1
- Imiquimod-Induced Psoriasis-Like Skin Inflammation in Mice Is Mediated via the IL-23/IL-17 Axis1
- Observations of psoriasis in the absence of therapeutic intervention identifies two unappreciated morphologic variants, thin-plaque and thick-plaque psoriasis, and their associated phenotypes.
- Cellular genomic maps help dissect pathology in human skin disease.
- Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris.
- Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene.
- Association of patient-reported psoriasis severity with income and employment.
- Clearance of severe psoriasis after allogenic bone marrow transplantation.
- MicroRNAs: Novel Regulators Involved in the Pathogenesis of Psoriasis?
- The major psoriasis susceptibility locus PSORS1 is not a risk factor for late-onset psoriasis.
- Psoriasis vulgaris lesions contain discrete populations of Th1 and Th17 T cells.
- Mouse models of psoriasis.
- Traditional systemic treatments have not fully met the needs of psoriasis patients: results from a national survey.
- The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response.
- Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses
Cited by
- Comparative Efficacy of Biologics in Psoriasis
- Psoriasis risk genes of the late cornified envelope-3 group are distinctly expressed compared with genes of other LCE groups.
- Upregulation and nuclear localization of TNF‐like Cytokine 1A (TL1A) and its receptors DR3 and DcR3 in psoriatic skin lesions
- Consensus guidelines for the management of plaque psoriasis.
- Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia
- Framingham Risk Score underestimates cardiovascular disease risk in severe psoriatic patients: Implications in cardiovascular risk factors management and primary prevention of cardiovascular disease
- The New Insight into the Role of Antimicrobial Proteins-Alarmins in the Immunopathogenesis of Psoriasis
- Evaluation of the Association Between CD143 Gene Polymorphism and Psoriasis
- Relationship between Helicobacter pylori infection and psoriasis
- Association of the PDE3A-SLCO1C1 locus with the response to anti-TNF agents in psoriasis
- The prevalence of NAFLD and NASH among patients with psoriasis in a tertiary care dermatology and rheumatology clinic
- Growth arrest-specific 6 and cardiometabolic risk factors in patients with psoriasis.
- RISK OF RETINAL VEIN OCCLUSION IN PATIENTS WITH PSORIASIS: A Population-Based Cohort Study
- IκBζ is a key driver in the development of psoriasis
- S100A7: A rAMPing up AMP molecule in psoriasis.
- Nail Psoriasis: A Review of Treatment Options
- Clinical and cytokine profile evaluation in Northeast Brazilian psoriasis plaque-type patients
- Psoriasis is associated with risk of obstructive sleep apnea independently from metabolic parameters and other comorbidities: a large hospital-based case-control study
- Quercetin ameliorates imiquimod‐induced psoriasis‐like skin inflammation in mice via the NF‐&kgr;B pathway
- Vascular endothelial growth factor (VEGF) gene polymorphisms (rs699947, rs833061, and rs2010963) and psoriatic risk in South Indian Tamils.
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