Molecular mechanisms of ROS production and oxidative stress in diabetes.
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Summary
The cellular and molecular origins and significance of ROS production, the molecular targets and responses describing how oxidative stress affects cell function including mechanisms of insulin secretion and action are reviewed from the point of view of possible application of novel diabetic therapies based on redox regulation.
- Type
- review
- Published
- 2016-12-15
- Cited by
- 742
- References
- 256
- Access
- Open access
- OpenAlex
- https://openalex.org/W2560781586
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:19963205
Keywords
Oxidative stress, Reactive oxygen species, Diabetes mellitus, Oxidative phosphorylation, Production (economics)
References
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- Brain injury with diabetes mellitus: evidence, mechanisms and treatment implications
- Preventive Effects of Pentoxifylline on the Development of Colonic Premalignant Lesions in Obese and Diabetic Mice
- The pancreas: Bandmaster of glucose homeostasis
- Daily Intake of Grape Powder Prevents the Progression of Kidney Disease in Obese Type 2 Diabetic ZSF1 Rats
- Vitamin D deficiency and diabetes.
- Nanotechnology for Electroanalytical Biosensors of Reactive Oxygen and Nitrogen Species.
- Inverse associations of HDL cholesterol and oxidized HDL with d-dimer in patients with type 2 diabetes mellitus.
- Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis
- The bioenergetics of inflammation: insights into obesity and type 2 diabetes
- Cerium dioxide nanoparticles possess anti-inflammatory properties in the conditions of the obesity-associated NAFLD in rats.
- Berberine Alleviates Oxidative Stress in Islets of Diabetic Mice by Inhibiting miR‐106b Expression and Up‐Regulating SIRT1
- The Role of Heparin Cofactor II in the Regulation of Insulin Sensitivity and Maintenance of Glucose Homeostasis in Humans and Mice
- Spirulina platensis prevents hyperglycemia in rats by modulating gluconeogenesis and apoptosis via modification of oxidative stress and MAPK-pathways.
- Alpha-lipoic Acid suppresses P2X receptor activities and visceral hypersensitivity to colorectal distention in diabetic rats
- Pancreatic mitochondrial complex I exhibits aberrant hyperactivity in diabetes
- Nitric oxide-heat shock protein axis in menopausal hot flushes: neglected metabolic issues of chronic inflammatory diseases associated with deranged heat shock response
- Food-Derived Antioxidant Polysaccharides and Their Pharmacological Potential in Neurodegenerative Diseases
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