Effect Of Isradipine On MES And Picrotoxin Induced Convulsion
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Summary
The anticonvulsant property may be by blockade of voltage dependent calcium channels by which calcium ions influx is blocked to stop the sequence of events leading to both the spread of epileptic discharge, cell damage and death.
- Type
- article
- Published
- 2010-01-01
- Cited by
- 2
- References
- 17
- OpenAlex
- https://openalex.org/W2504139683
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:157280003
Keywords
Isradipine, Picrotoxin, Convulsion, Diazepam, Anticonvulsant
References
- Influence of flunarizine, nicardipine and nimodipine on the anticonvulsant activity of different antiepileptic drugs in mice.
- Nifedipine has paradoxical effects on the development of kindling but not on kindled seizures in amygdala-kindled rats.
- Recent advances in epilepsy. I
- Cellular and synaptic physiology and epileptogenesis of developing rat neocortical neurons in vitro.
- Calcium and epileptogenesis
- Effect of various calcium channel blockers on three different models of limbic seizures in rats.
- Suppression of epileptiform burst discharges in CA3 neurons of rat hippocampal slices by the organic calcium channel blocker, verapamil
- Influence of Ginkgo Biloba on the effect of anticonvulsants
- Epileptiform activity induced by low chloride medium in the CA1 subfield of the hippocampal slice.
- A molecular approach to the calcium signal in brain: relationship to synaptic modulation and seizure discharge.
- A comparative experimental study of the anticonvulsant effect of three calcium channel blockers in albino mice
Cited by
- Design, synthesis and evaluation of dialkyl 4-(benzo[d][1,3]dioxol-6-yl)-1,4-dihydro-2,6-dimethyl-1-substituted pyridine-3,5-dicarboxylates as potential anticonvulsants and their molecular properties prediction.
- Neuroprotective Effect of Lercanidipine- A Novel Calcium Channel Blocker in Albino Mice.
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