Raised viral load in patients with viral suppression on highly active antiretroviral therapy: transient increase or treatment failure?
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Summary
Transient increases and virological failure were more common in those with greater drug experience, and those with initial raised viral load values of more than 400 copies/ml were more likely to have a sustained increase and become Virological failures.
- Type
- article
- Published
- 2002-03-08
- Cited by
- 49
- References
- 18
- OpenAlex
- https://openalex.org/W2334605091
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:32392182
Keywords
Viral load, Medicine, Viral disease, Antiretroviral therapy, Cohort
References
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- Decay of cell-associated HIV-1 DNA correlates with residual replication in patients treated during acute HIV-1 infection
- Transient Relapses (“Blips”) of Plasma HIV RNA Levels During HAART Are Associated With Drug Resistance
- The contribution of assay variation and biological variation to the total variability of plasma HIV-1 RNA measurements. The Women Infant Transmission Study Clinics. Virology Quality Assurance Program.
- The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy
- Decay characteristics of HIV-1-infected compartments during combination therapy
- Prevalence and predictive value of intermittent viremia with combination hiv therapy.
- Effect of influenza vaccination on viral replication and immune response in persons infected with human immunodeficiency virus receiving potent antiretroviral therapy.
- Adherence to Protease Inhibitor Therapy and Outcomes in Patients with HIV Infection
- Comparison of the safety, vaccine virus shedding, and immunogenicity of influenza virus vaccine, trivalent, types A and B, live cold-adapted, administered to human immunodeficiency virus (HIV)-infected and non-HIV-infected adults.
- Guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents. U.S. Department of Health and Human Services (DHHS).
- Transient Relapses (“Blips”) of Plasma HIV RNA Levels During HAART Are Associated With Drug Resistance
Cited by
- HIV virological rebounds but not blips predict liver fibrosis progression in antiretroviral-treated HIV/hepatitis C virus-coinfected patients
- A Control Theoretic Approach to HIV/AIDS Drug Dosage Design and Timing the Initiation of Therapy
- Multi-class support vector machines for modeling HIV/AIDS treatment adherence using patient data
- Transient Viral Load Increases in HIV-Infected Children in the UK and Ireland: What do They Mean?
- Human Immunodeficiency Virus (HIV)- Blood Interactions in Antiretroviral Drugs Environment—Surface Thermodynamics Approach
- Genotypic Resistance and Immunologic Outcomes Among HIV-1-Infected Women With Viral Failure
- Persistent low‐level viraemia and virological failure in HIV‐1‐infected patients treated with highly active antiretroviral therapy
- The Clinical Interpretation of Viral Blips in HIV Patients Receiving Antiviral Treatment: Are We Ready to Infer Poor Adherence?
- Defining Treatment Failure in Resource-Rich Settings
- Temporal Association Between Incident Tuberculosis and Poor Virological Outcomes in a South African Antiretroviral Treatment Service
- Intermittent HIV-1 Viremia (Blips) and Virological Failure in a Cohort of People Living with HIV from São Paulo, Brazil
- The Significance of HIV Viral Load Assay Precision: A Review of the Package Insert Specifications of Two Commercial Kits
- Gender Differences in HIV-1 RNA Rebound Attributed to Incomplete Antiretroviral Adherence Among HIV-Infected Patients in a Population-Based Cohort
- Influence of a Vaccination Schedule on Viral Load Rebound and Immune Responses in Successfully Treated HIV-Infected Patients
- HIV viral load: the myth of the undetectable?
- Plasma levels of B-lymphocyte stimulator increase with HIV disease progression
- No evidence of an association between transient HIV viremia ("Blips") and lower adherence to the antiretroviral medication regimen.
- Definition of loss of virological response in trials of antiretroviral drugs
- Drug switching and virologic-based endpoints in trials of antiretroviral drugs for HIV infection
- The Significance of Low-Level Plasma HIV Viral Load on COBAS TaqMan® HIV-1 Assays for Patients with Undetectable Plasma Viral Load on COBAS Amplicor® Monitor Version 1.5
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