Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.
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Summary
It is reported that the nuclear m(6)A reader protein YTHDC1 impacts mRNA splicing, providing a transcriptome-wide glance of splicing changes affected by this mRNA methylation reader protein.
- Type
- letter
- Published
- 2016-06-01
- Cited by
- 1,929
- References
- 10
- Access
- Open access
- OpenAlex
- https://openalex.org/W2314476006
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3581097
Keywords
RNA splicing, Biology, Messenger RNA, Alternative splicing, Transcriptome
References
- HNRNPA2B1 is a mediator of m6A-dependent nuclear RNA processing events
- N6-methyladenosine Modulates Messenger RNA Translation Efficiency
- The YTH Domain Is a Novel RNA Binding Domain*
- m6A-dependent regulation of messenger RNA stability
- N6-methyl-adenosine (m6A) marks primary microRNAs for processing
- Structural basis for selective binding of m6A RNA by the YTHDC1 YTH domain.
- Cloning of a gene, YT521, for a novel RNA splicing-related protein induced by hypoxia/reoxygenation.
- Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
- The intranuclear localization and function of YT521-B is regulated by tyrosine phosphorylation.
- Faculty Opinions recommendation of Nuclear m(6)A Reader YTHDC1 Regulates mRNA Splicing.
- Nuclear m6A Reader YTHDC1 Regulates mRNA Splicing
Cited by
- METTL3 Gains R/W Access to the Epitranscriptome.
- Maintenance of Genome Stability
- Update: Mechanisms underlying N6-methyladenosine modification of eukaryotic mRNA
- Arabidopsis m6A demethylase activity modulates viral infection of a plant virus and the m6A abundance in its genomic RNAs
- Reduced nucleic acid methylation impairs meiotic maturation and developmental potency of pig oocytes.
- The untranslated regions of mRNAs in cancer
- Nuclear TARBP2 drives oncogenic dysregulation of RNA splicing and decay
- N 6-Methyladenosine Methyltransferases and Demethylases: New Regulators of Stem Cell Pluripotency and Differentiation
- Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex
- Deciphering the epitranscriptome: A green perspective
- m6A: Signaling for mRNA splicing
- YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex
- m6A RNA methylation promotes XIST-mediated transcriptional repression
- Structural insights into the molecular mechanism of the m6A writer complex
- Serine/Arginine-Rich Splicing Factor 3 and Heterogeneous Nuclear Ribonucleoprotein A1 Regulate Alternative RNA Splicing and Gene Expression of Human Papillomavirus 18 through Two Functionally Distinguishable cis Elements
- Identification of replication-dependent and replication-independent linker histone complexes: Tpr specifically promotes replication-dependent linker histone stability
- ALKBH1-Mediated tRNA Demethylation Regulates Translation
- Dynamic proteomics of HSV1 infection reveals molecular events that govern non-stochastic infection outcomes
- Post-transcriptional gene regulation by mRNA modifications
- Post-transcriptional modifications in development and stem cells
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