Reduced nucleic acid methylation impairs meiotic maturation and developmental potency of pig oocytes.
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Summary
Chemical induced reduction of nucleic acid m6A methylation during pig oocyte meiosis could impair meiotic maturation and subsequent development potency, possibly through down-regulating pluripotency marker Lin28 mRNA abundance and disturbing MPF-regulated chromosome/spindle organization.
- Type
- book
- Published
- 2018-11-01
- Cited by
- 35
- References
- 43
- OpenAlex
- https://openalex.org/W30165304
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:52135700
Keywords
String (physics), Control (management), Computer science, History, Theoretical physics
References
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Cited by
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- Whole-Genome Methylation Analysis Reveals Epigenetic Variation in Cloned and Donor Pigs
- N6-methyladenosine demethylases Alkbh5/Fto regulate cerebral ischemia-reperfusion injury
- Effects of oxygen concentrations on developmental competence and transcriptomic profile of yak oocytes
- Wilms' tumor 1-associating protein contributes to psoriasis by promoting keratinocytes proliferation via regulating cyclinA2 and CDK2.
- m6a Methylation Inhibition by Cycloleucine Impaired Porcine Oocyte Meiosis and Early Embryonic Development via Remodeling Histone Modifications and Altering Metabolism Related Gene Expression in Blastocysts
- Decreased expression of m6A demethylase FTO in ovarian aging
- The Effect of Huyang Yangkun Formula on N6-methyladenosine Modification in 4-vinylcyclohexene diepoxide Induced Premature Ovarian Insufficiency Rats
- METTL3-mediated m6A methylation negatively modulates autophagy to support porcine blastocyst development‡
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- Loss of WTAP Impairs Early Parthenogenetic Embryo Development
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- Metabolic profiling of preovulatory follicular fluid in jennies.