Two RNA-binding motifs in the double-stranded RNA-activated protein kinase, DAI.
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- Type
- article
- Published
- 1992-12-01
- Cited by
- 248
- References
- 57
- Access
- Open access
- OpenAlex
- https://openalex.org/W2168409709
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3469362
Keywords
Biology, RNA silencing, RNA, RNA-binding protein, RNA recognition motif
References
- Purification of the eukaryotic initiation factor 2-eukaryotic initiation factor 2B complex and characterization of its guanine nucleotide exchange activity during protein synthesis initiation.
- Human p68 kinase exhibits growth suppression in yeast and homology to the translational regulator GCN2.
- Effects of mutations in stem and loop regions on the structure and function of adenovirus VA RNAI.
- Identification of the double-stranded RNA-binding domain of the human interferon-inducible protein kinase.
- Growth-related expression of a double-stranded RNA-dependent protein kinase in 3T3 cells.
- Activation of 2',5'-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells by 2'-O-methylated poly (inosinic acid) . poly(cytidylic acid), Correlations with interferon-inducing activity.
- Inhibition of protein synthesis by double-stranded RNA and phosphorylation of initiation factor, eIF-2.
- Protein phosphorylation controls translation rates.
- A GDP/GTP exchange factor essential for eukaryotic initiation factor 2 cycling in Ehrlich ascites tumor cells and its regulation by eukaryotic initiation factor 2 phosphorylation.
- Reduced activity of the interferon-induced double-stranded RNA-dependent protein kinase during a heat shock stress.
- Functional dissection of adenovirus VAI RNA
- Autophosphorylation of the protein kinase dependent on double-stranded RNA.
- Structural requirements of double-stranded RNA for the activation of 2',5'-oligo(A) polymerase and protein kinase of interferon-treated HeLa cells.
- Antibodies: A Laboratory Manual
- Structure and regulation of eukaryotic initiation factor eIF-2. Sequence of the site in the alpha subunit phosphorylated by the haem-controlled repressor and by the double-stranded RNA-activated inhibitor.
- Mechanism of interferon action. Purification and substrate specificities of the double-stranded RNA-dependent protein kinase from untreated and interferon-treated mouse fibroblasts.
- Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression
- Partial characterization of a cellular factor that regulates the double-stranded RNA-dependent eIF-2 alpha kinase in 3T3-F442A fibroblasts
- Phosphorylation of initiation factor 2α by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast
- Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2α kinase
Cited by
- Mutagenic Analysis of Double-stranded RNA Adenosine Deaminase, a Candidate Enzyme for RNA Editing of Glutamate-gated Ion Channel Transcripts (*)
- Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase
- In vitro analysis of virus-associated RNA I (VAI RNA): inhibition of the double-stranded RNA-activated protein kinase PKR by VAI RNA mutants correlates with the in vivo phenotype and the structural integrity of the central domain
- Site-directed mutagenesis of the double-stranded RNA binding domain of bacterially-expressed sigma 3 reovirus protein.
- Specific Mutations Near the Amino Terminus of Double-stranded RNA-dependent Protein Kinase (PKR) Differentially Affect Its Double-stranded RNA Binding and Dimerization Properties*
- The apoptosis pathway triggered by the interferon-induced protein kinase PKR requires the third basic domain, initiates upstream of Bcl-2, and involves ICE-like proteases.
- The murine PKR tumor suppressor gene is rearranged in a lymphocytic leukemia.
- Post-transcriptional control of gene expression during spermatogenesis.
- A dynamically tuned double‐stranded RNA binding mechanism for the activation of antiviral kinase PKR
- Functional control of HIV-1 post-transcriptional gene expression by host cell factors
- Interferon action and the double-stranded RNA-dependent enzymes ADAR1 adenosine deaminase and PKR protein kinase.
- Identification and functional characterisation of novel APC/C interacting proteins
- Structure of the dsRNA binding domain of E. coli RNase III.
- Structure and function of the protein kinase R.
- NMR solution structure of a dsRNA binding domain from Drosophila staufen protein reveals homology to the N‐terminal domain of ribosomal protein S5.
- Structural characterization of the minimal human RISC-loading complex
- Sequence-non-specific effects of RNA interference triggers and microRNA regulators
- Mechanistic Analysis of Activation of the Innate Immune Sensor PKR by Bacterial RNA
- Germ Cell Development, Division, Disruption and Death
- The role of dsRNA in nuclear differentiation and remodeling in the ciliate, Tetrahymena thermophila
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