The NF-kappa B and I kappa B proteins: new discoveries and insights.
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Summary
Excitement in NF-kappa B research has been generated by the first report of a crystal structure for one form of NF-Kappa B, the first gene knockout studies for different forms ofNF-kB and of I kappaB, and the implications for therapies of diseases thought to involve the inappropriate activation of NF.
- Type
- review
- Published
- 1996-04-01
- Cited by
- 1,904
- References
- 0
- OpenAlex
- https://openalex.org/W2166781237
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10513523
Keywords
Biology, NF-κB, Transcription factor, IκBα, Cell biology
References
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- A striking similarity in the organization of the E-selectin and beta interferon gene promoters.
- NF-kappa B sites function as positive regulators of expression of the translocated c-myc allele in Burkitt's lymphoma.
- Interleukin-10-deficient mice develop chronic enterocolitis
- Distinct mechanisms for regulation of the interleukin-8 gene involve synergism and cooperativity between C/EBP and NF-kappa B.
- Human T-cell leukemia virus type I Tax activation of NF-kappa B/Rel involves phosphorylation and degradation of I kappa B alpha and RelA (p65)-mediated induction of the c-rel gene.
- Both N- and C-terminal domains of RelB are required for full transactivation: role of the N-terminal leucine zipper-like motif.
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- Thymocyte-Thymic Epithelial Cell Interaction Leads to High-Level Replication of Human Immunodeficiency Virus Exclusively in Mature CD4+ CD8− CD3+ Thymocytes: a Critical Role for Tumor Necrosis Factor and Interleukin-7
- Akt Suppresses Apoptosis by Stimulating the Transactivation Potential of the RelA/p65 Subunit of NF-κB
- Vasoactive intestinal peptide and pituitary adenylate cyclase‐activating polypeptide inhibit chemokine production in activated microglia
- Development of a High-Throughput Plate-Based Chemiluminescent Transcription Factor Assay
- Glucosyltransferases of Viridans Group Streptococci Modulate Interleukin-6 and Adhesion Molecule Expression in Endothelial Cells and Augment Monocytic Cell Adherence
- Nicotine Treatment Alters NF-κB Expression in Human Cytomegalovirus-Infected ARPE-19 Cells
- Expression of CCL17 and CCL22 by latent membrane protein 1‐positive tumor cells in age‐related Epstein–Barr virus‐associated B‐cell lymphoproliferative disorder
- Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin.
- Glutaredoxin regulation of pro -inflammatory responses in a model of diabetic retinopathy
- Ligand-Directed AAVP to Deliver a Therapeutic Transgene to Neuroendocrine Tumors of the Pancreas
- Mitochondrial Regulation of Cell Cycle and Proliferation
- Angiopoietin-like protein 2 mediates endotoxin-induced acute inflammation in the eye
- Identification of novel compounds that enhance colon cancer cell sensitivity to inflammatory apoptotic ligands
- Involvement of Nuclear Factor-κB in Endothelin-A-Receptor–Induced Proliferation and Inhibition of Apoptosis
- Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling
- Downregulation of diacylglycerol kinase ζ enhances activation of cytokine-induced NF-κB signaling pathway.
- Apocynin ameliorates endotoxin-induced acute lung injury in rats.
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