Influence of Life Stress on Depression: Moderation by a Polymorphism in the 5-HTT Gene
Explore this paper's citation graph
Summary
Evidence of a gene-by-environment interaction is provided, in which an individual's response to environmental insults is moderated by his or her genetic makeup.
- Type
- article
- Published
- 2003-07-18
- Cited by
- 7,953
- References
- 43
- OpenAlex
- https://openalex.org/W2162196924
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:3014935
Keywords
Serotonin transporter, Moderation, Depression (economics), Allele, Polymorphism (computer science)
References
- Excessive Activation of Serotonin (5-HT) 1B Receptors Disrupts the Formation of Sensory Maps in Monoamine Oxidase A and 5-HT Transporter Knock-Out Mice
- Developing novel treatments for mood disorders: accelerating discovery.
- Sex and depression in the National Comorbidity Survey. I: Lifetime prevalence, chronicity and recurrence.
- Genetic and population perspectives on life events and depression
- Neuropsychology Mental Structure
- Pharmacogenomics: translating functional genomics into rational therapeutics.
- Diathesis-stress theories in the context of life stress research: implications for the depressive disorders.
- An epidemic of complex dysmorphologic syndromes in southeast Spain?
- Development and natural history of mood disorders.
- Role of Genotype in the Cycle of Violence in Maltreated Children
- Adolescent life events as predictors of adult depression.
- Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region
- Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study.
- Stressful life events and genetic liability to major depression: genetic control of exposure to the environment?
- Causal relationship between stressful life events and the onset of major depression.
- Stressful life events, genetic liability, and onset of an episode of major depression in women.
- The effects of stressful life events on depression.
- The endophenotype concept in psychiatry: etymology and strategic intentions.
- Molecular Genetics and the Human Personality
- Serotonin Transporter Genetic Variation and the Response of the Human Amygdala
Cited by
- An Overview of Psychological and Neurobiological Mechanisms by which Early Negative Experiences Increase Risk of Mood Disorders.
- Comorbid anxiety and depression.
- [Evolutionary concepts of affective disorders].
- Two models of job stress and depressive symptoms
- Reducing the Burden of Depression
- A model of the neural basis of predecisional processes: the fronto-limbic information acquisition network
- Implication du BDNF dans l'étiopathogenèse et le traitement des troubles anxio-dépressifs : aspects précliniques.
- Physiological Stress Reactivity in Late Pregnancy
- Deprivation of parenting disrupts development of homeostatic and reward systems in marmoset monkey offspring.
- A case-control and family-based association study of the 5-HTTLPR in pediatric-onset depressive disorders.
- Deep brain stimulation for treatment-resistant depression.
- Meta-analysis in psychiatric genetics
- Serotonin transporter gene polymorphism (5-HTTLPR) and emotional response to auditory hallucinations in schizophrenia.
- 10-year research update review: the epidemiology of child and adolescent psychiatric disorders: I. Methods and public health burden.
- Evolution and depression: issues and implications
- Neuroticism Mediates the Association of the Serotonin Transporter Gene with Lifetime Major Depression
- Identifying interactions between genes and early environment in the mouse
- Genotype x Environment interaction in psychopathology: fact or artifact?
- The HPA axis and perinatal depression: a hypothesis
- Inactivation of 5HT transport in mice: modeling altered 5HT homeostasis implicated in emotional dysfunction, affective disorders, and somatic syndromes.
Related papers
- Who exactly is the moderator? A consideration of online knowledge management network moderation in educational organisations
- Reconsidering Self-Moderation
- How Does Intensity of Social Network Sites Use Moderate Cybervictimization? Understanding the Factors and Conditions Using an R-Based Tool for Probing Moderation Effects
- EXPATRIATES' INTERACTION ADJUSTMENT: THE DIRECT AND MODERATOR EFFECTS OF CULTURE OF ORIGIN
- The Role of Higher Education Integrated with Religious Moderation
- How do people define moderation?
- Assessing moderation effects with a heterogeneous moderated regression analysis
- Moderation of Religious Madrasah Teachers