Identification of mammalian microRNA host genes and transcription units.
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Summary
It is strongly suggested that miRNAs are transcribed in parallel with their host transcripts, and that the two different transcription classes of miRNAAs ('exonic' and 'intronic') identified here may require slightly different mechanisms of biogenesis.
- Type
- article
- Published
- 2004-10-01
- Cited by
- 2,189
- References
- 48
- Access
- Open access
- OpenAlex
- https://openalex.org/W2161149887
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:16226927
Keywords
Biology, Genetics, Gene, Genome, Sanger sequencing
References
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- Identification and characterization of human BIC, a gene on chromosome 21 that encodes a noncoding RNA.
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Cited by
- Intron-mediated RNA interference, intronic microRNAs, and applications.
- RARs and microRNAs.
- Gene expression regulators —MicroRNAs
- Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes.
- Therapeutic RNA interference for neurodegenerative diseases: From promise to progress.
- Genomic Organization of Zebrafish microRNAs
- Human cytomegalovirus microRNAs.
- Intron-mediated RNA interference and microRNA biogenesis.
- C19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts
- MicroRNAs in breast cancer
- Determination of MiRNA Targets in Skeletal Muscle Cells
- Regulatory RNAs in mammals.
- Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain
- Exceptional stories of microRNAs
- [DNA methylation status of miR-126 and its host gene EGFL7 in CD4+ T cells from patients with systemic lupus erythematosus].
- Dissecting the telomere-independent pathways underlying human cellular senescence
- microRNAs: a newly described class of encoded molecules that play a role in health and disease.
- MicroRNAs: key components of immune regulation.
- Regulatory network of microRNAs and genes in testicular cancer.
- The Versatile Role of microRNA-30a in Human Cancer
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