The Interaction of Selection and Linkage. I. General Considerations; Heterotic Models.
Explore this paper's citation graph
Summary
The results of these investigations were sufficient to show that even for relatively simple cases (two loci, simple symmetrical selective values) linkage might have profound effects on the course of natural selection and, pari passu, natural selection may have major effect on the distribution of coupling and repulsion linkage in a population.
- Type
- article
- Published
- 1964-01-10
- Cited by
- 1,879
- References
- 4
- Access
- Open access
- OpenAlex
- https://openalex.org/W2159487337
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8858710
Keywords
Biology, Heterotic string theory, Linkage (software), Selection (genetic algorithm), Genetics
References
Cited by
- Analytical Methods for Immunogenetic Population Data
- TNF2, a polymorphism of the tumour necrosis‐α gene promoter, is a component of the celiac disease major histocompatibility complex haplotype
- On Fisher's exact test for detecting gametic disequilibrium between DNA polymorphisms
- Human RAGE GLY82SER dimorphism and HLA class II DRB1-DQA1-DQB1 haplotypes in type 1 diabetes.
- Analysis of the Ser786Pro interleukin-4 receptor alpha allelic variant in allergic and nonallergic asthma and its functional consequences.
- HLA-DPA1 and DPB1 polymorphism in four Pacific Islands populations determined by sequencing based typing.
- Association of the human adiponectin gene and insulin resistance
- High-Resolution Joint Linkage Disequilibrium and Linkage Mapping of Quantitative Trait Loci Based on Sibship Data
- Genetic isolates in Corsica (France): linkage disequilibrium extension analysis on the Xq13 region
- Interleukin 18 promoter polymorphisms are not strongly associated with type I diabetes in a UK population
- New concepts for distinguishing the hidden patterns of linkage disequilibrium which underlie association between genotypes and complex phenotypes.
- Factors affecting statistical power in the detection of genetic association.
- Extensive intragenic recombination and patterns of linkage disequilibrium at the CSN3 locus in European rabbit
- Characteristics of the β-Globin Gene Cluster Haplotypes of Three Han Chinese Populations at Beijing, Xi’an, and Kunming as Compared with Those of Other Asian Populations
- Rapid rise and fall of selfish sex-ratio X chromosomes in Drosophila simulans: spatiotemporal analysis of phenotypic and molecular data.
- Associations between Polymorphisms Related to Calcium Metabolism and Human Height: The Tromsø Study
- The admixed population structure in Danish Jersey dairy cattle challenges accurate genomic predictions.
- Cooperation, conformity, and the coevolutionary problem of trait associations.
- Designing an optimum genetic association study using dense SNP markers and family-based sample.
- Genomic selection in dairy cattle
Related papers
- Meta-Analysis of Genome-Wide Linkage Scans of Attention Deficit Hyperactivity Disorder
- Linkage group IV in the Syrian hamster: spontaneous seizure and jute.
- Impact of overlapping recruitment on linkage analysis of complex disorders: simulation studies.
- Joint segregation and linkage analysis of a quantitative trait compared to separate analyses
- Use of LINKAGE Programs for Linkage Analysis
- Five new linkage groups in the canine linkage map.
- Analysis of the linkage JK-IGK, MNS-GC and of two other possible linkage groups.
- Autosomal dominant ophthalmologic disorders and linkage.
- Joint segregation and linkage analysis of a quantitative trait compared to separate analyses