Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial.
Explore this paper's citation graph
Summary
A treatment strategy directed at normalisation of the induced sputum eosinophil count reduces asthma exacerbations and admissions without the need for additional anti-inflammatory treatment.
- Type
- article
- Published
- 2002-11-30
- Cited by
- 1,776
- References
- 30
- OpenAlex
- https://openalex.org/W2154263136
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10571101
Keywords
Sputum, Medicine, Eosinophil, Asthma, Internal medicine
References
- Impaired perception of dyspnea in patients with severe asthma. Relation to sputum eosinophils.
- Exhaled and nasal nitric oxide measurements: recommendations. The European Respiratory Society Task Force.
- How should cost data in pragmatic randomised trials be analysed?
- Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response.
- Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. The AMPUL Study Group.
- Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics.
- Non-eosinophilic corticosteroid unresponsive asthma.
- Measuring quality of life in asthma.
- Age specific trends in asthma mortality in England and Wales, 1983-95: results of an observational study
- Montelukast reduces airway eosinophilic inflammation in asthma: a randomized, controlled trial.
- Mast-cell infiltration of airway smooth muscle in asthma.
- Dissociation between airway inflammation and airway hyperresponsiveness in allergic asthma.
- Eosinophils in asthma and other allergic diseases.
- Prednisone-dependent asthma: inflammatory indices in induced sputum.
- Changes in sputum eosinophils predict loss of asthma control.
- Risk factors and costs associated with an asthma attack
- Heterogeneity of airway inflammation in persistent asthma : evidence of neutrophilic inflammation and increased sputum interleukin-8.
- Proceedings of the ATS workshop on refractory asthma: current understanding, recommendations, and unanswered questions. American Thoracic Society.
- Physician-diagnosed asthma and drug utilization in the European Community Respiratory Health Survey.
- Airway structure and inflammatory cells in fatal attacks of asthma.
Cited by
- Cytokines and cytokine-specific therapy in asthma.
- Effects of a short course of inhaled corticosteroids in noneosinophilic asthmatic subjects.
- New insights into the relationship between airway inflammation and asthma.
- Asthma exacerbations and inhaled corticosteroids.
- Effects of hydrofluoroalkane formulations of ciclesonide 400 microg once daily vs fluticasone 250 microg twice daily on methacholine hyper-responsiveness in mild-to-moderate persistent asthma.
- Assessment of asthma control in a general population of asthmatics*
- Is the neutrophil a worthy target in severe asthma and chronic obstructive pulmonary disease?
- Methods used in clinical development of novel anti-asthma therapies.
- Management of asthma in adults
- Simplified detection of eosinophils in induced sputum
- Untangling asthma phenotypes and endotypes
- Bronchodilator response as a hallmark of uncontrolled asthma: a randomised clinical trial
- Exhaled nitric oxide and screening for occupational asthma in two at-risk sectors: bakery and hairdressing.
- Identification of responders to inhaled corticosteroids in a chronic obstructive pulmonary disease population using cluster analysis
- Priorities for future research into asthma diagnostic tools: A PAN‐EU consensus exercise from the European asthma research innovation partnership (EARIP)
- Oral corticosteroid-dependent asthma: current knowledge and future needs
- Fibroblast‐specific integrin‐alpha V differentially regulates type 17 and type 2 driven inflammation and fibrosis
- Overcoming Gaps in the Management of Asthma in Older Patients
- Endotype Driven Treatment of Asthma
- Induced sputum in childhood asthma.
Related papers
- [Supplementary notes on securing sputum washing and bacterial culture methods for the purpose of isolating the causative agents in respiratory infections].
- The feasibility study of two sputum specimens instead of three copies of sputum specimens smear method
- Diagnosis of Pulmonary Tuberculosis in less Sputum Producing or Sputum Smear Negative Cases: A Prospective Study in a Tertiary Care Hospital
- Comparison on resulte of sputum culture and sputum smear from patients in critical medicine department
- Some factors influencing quality of spontaneous or induced sputum for inflammatory cell analysis.
- The role of macroscopic sputum quality assessments to optimise sputum testing for tuberculosis.
- Application of induced sputum in sputum specimen collection among children with pneumonia
- Effects of Different Gathering Methods on Sputum Culture Specimen Examination in Children with Pneumonia
- Identification of COPD Inflammatory Endotypes Using Repeated Sputum Eosinophil Counts
- P181 Better asthma control with montelukast than salmeterol in Arg-16 homozygous children with asthma