Fibroblast‐specific integrin‐alpha V differentially regulates type 17 and type 2 driven inflammation and fibrosis
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Summary
Findings suggest dual targeting of integrin‐alpha V and type 2 pathways may be needed to ameliorate fibrosis and prevent rebound of opposing pro‐fibrotic and inflammatory mechanisms.
- Type
- article
- Published
- 2019-01-24
- Cited by
- 20
- References
- 64
- OpenAlex
- https://openalex.org/W30536905
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:54480998
Keywords
Materials science
References
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- Pax7, Pax3 and Mamstr Genes are Involved in Skeletal Muscle Impaired Regeneration of dy2J/dy2J Mouse Model of Lama2-CMD.
- Controlling Immunity and Inflammation through Integrin-Dependent Regulation of TGF-β.
- TGF-β1 - A truly transforming growth factor in fibrosis and immunity.
- HDAC inhibitor sodium butyrate prevents allergic rhinitis and alters lncRNA and mRNA expression profiles in the nasal mucosa of mice
- Integrin-Ligand Interactions in Inflammation, Cancer, and Metabolic Disease: Insights Into the Multifaceted Roles of an Emerging Ligand Irisin
- FIBROSIS: FROM MECHANISMS TO MEDICINES
- Perivascular stromal cells: Directors of tissue immune niches
- Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis
- Validation of Specific and Reliable Genetic Tools to Identify, Label, and Target Cardiac Pericytes in Mice
- Global gene expression responses of Atlantic salmon skin to Moritella viscosa
- Molecular Modeling Insights into the Structure and Behavior of Integrins: A Review
- New insights into fibrotic signaling in hepatocellular carcinoma
- Distinct fibroblast functions associated with fibrotic and immune-mediated inflammatory diseases and their implications for therapeutic development
- The fate and role of the pericytes in myocardial diseases
- Roles of focal adhesion proteins in obesity related metabolic syndrome.
- Inflammatory bowel disease and extracellular matrix: when victim becomes double agent
- Unleashing innovative cross-organ fibrosis therapies by harnessing the omics revolution
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