Chemokines and chemokine receptors: positioning cells for host defense and immunity.
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Summary
This review focuses on recent advances in understanding how the chemokine system orchestrates immune cell migration and positioning at the organismic level in homeostasis, in acute inflammation, and during the generation and regulation of adoptive primary and secondary immune responses in the lymphoid system and peripheral nonlymphoid tissue.
- Type
- review
- Published
- 2014-03-21
- Cited by
- 1,878
- References
- 265
- Access
- Open access
- OpenAlex
- https://openalex.org/W2153960708
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10579265
Keywords
Biology, Chemokine receptor, Chemokine, CCL18, Immune system
References
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- Eotaxin induces a rapid release of eosinophils and their progenitors from the bone marrow.
- Immobilized chemokine fields and soluble chemokine gradients cooperatively shape migration patterns of dendritic cells.
- Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell–dendritic cell interaction
- Innate lymphoid cells — how did we miss them?
- The Subpopulation of CD4+CD25+ Splenocytes That Delays Adoptive Transfer of Diabetes Expresses L-Selectin and High Levels of CCR71
- CD26/dipeptidyl-peptidase IV down-regulates the eosinophil chemotactic potency, but not the anti-HIV activity of human eotaxin by affecting its interaction with CC chemokine receptor 3.
- Human Th17 Cells Share Major Trafficking Receptors with Both Polarized Effector T Cells and FOXP3+ Regulatory T Cells
- Inflammatory chemokine receptors regulate CD8+ T cell contraction and memory generation following infection
- Monocyte chemoattractant protein-1 and CCR2 interactions are required for IFN-alpha/beta-induced inflammatory responses and antiviral defense in liver.
- Regulation of Trafficking Receptor Expression in Human Forkhead Box P3+ Regulatory T Cells1
- Coordinated Involvement of Mast Cells and T Cells in Allergic Mucosal Inflammation: Critical Role of the CC Chemokine Ligand 1:CCR8 Axis
- Chemokine receptor CXCR3 facilitates CD8+ T cell differentiation into short-lived effector cells leading to memory degeneration
- C3a and C5a are chemotaxins for human mast cells and act through distinct receptors via a pertussis toxin-sensitive signal transduction pathway.
- MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditions
- Visualizing the generation of memory CD4 T cells in the whole body
- CD1d-Restricted NKT Cells Express a Chemokine Receptor Profile Indicative of Th1-Type Inflammatory Homing Cells 1
Cited by
- Moving to the suburbs: T‐cell positioning within lymph nodes during activation and memory
- Chemokine-guided cell positioning in the lymph node orchestrates the generation of adaptive immune responses
- CCR2 Regulates the Immune Response by Modulating the Interconversion and Function of Effector and Regulatory T Cells
- Pregnancy and spontaneous fetal loss: A pig perspective
- Cytokine and Chemokine Profiling in Patients with Hand, Foot and Mouth Disease in Singapore and Malaysia
- Description of organ-specific phenotype, and functional characteristics of tissue resident lymphocytes from liver transplantation donor and research on immune tolerance mechanism of liver
- The Orphan G Protein-coupled Receptor 75 Signaling is Activated by the Chemokine CCL5
- Probiotic Cell-Free Supernatants Exhibited Anti-Inflammatory and Antioxidant Activity on Human Gut Epithelial Cells and Macrophages Stimulated with LPS
- Comparison of rheumatoid arthritis (RA) and osteoarthritis (OA) based on microarray profiles of human joint fibroblast‐like synoviocytes
- Increased CCL17 serum levels are associated with improved survival in advanced melanoma
- Immune regulation at the fetal‐maternal interface with focus on decidual macrophages
- A Linear Epitope in the N-Terminal Domain of CCR5 and Its Interaction with Antibody
- Interferon-gamma Mediated Host Responses to Enteric Pathogen, Citrobacter rodentium
- Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges
- Non-redundant Requirement for CXCR3 Signaling during Tumoricidal T Cell Trafficking across Tumor Vascular Checkpoints
- CsCCL17, a CC chemokine of Cynoglossus semilaevis, induces leukocyte trafficking and promotes immune defense against viral infection.
- Subpopulations of M-MDSCs from mice infected by an immunodeficiency-causing retrovirus and their differential suppression of T- vs B-cell responses
- CMV Chemokines and Co-infection: A Dissemination Plot that Peptides Can Foil
- MicroRNAs in skin immunity and psoriasis
- Fever and the thermal regulation of immunity: the immune system feels the heat
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