Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20.
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Summary
IL-20 administration to normal mice significantly increased only multipotential progenitor cells, demonstrating that IL-20 significantly influences hematopoiesis, with specificity toward multipotentials progenitors, the first cytokine with such specificity identified.
- Type
- article
- Published
- 2003-11-01
- Cited by
- 50
- References
- 23
- Access
- Open access
- OpenAlex
- https://openalex.org/W2143307899
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13356118
Keywords
Progenitor cell, Haematopoiesis, Biology, Cell biology, Megakaryocyte
References
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- Cutting Edge: STAT Activation By IL-19, IL-20 and mda-7 Through IL-20 Receptor Complexes of Two Types1
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- Myelosuppressive Cytokines and Peptides
- Current protocols in immunology
Cited by
- The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis
- Neutralizing Anti-IL20 Antibody Treatment Significantly Modulates Low Grade Inflammation without Affecting HbA1c in Type 2 Diabetic db/db Mice
- Cutting Edge: IL-26 Signals through a Novel Receptor Complex Composed of IL-20 Receptor 1 and IL-10 Receptor 2 1
- Tissue microarray analysis of interleukin-20 expression.
- Evolution of the Class 2 cytokines and receptors, and discovery of new friends and relatives.
- Cytokines and autoimmunity: redundancy defines their complex nature.
- Interleukins, from 1 to 37, and interferon-γ: receptors, functions, and roles in diseases.
- Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis.
- Interleukin (IL)‐19, IL‐20 and IL‐24 are produced by and act on keratinocytes and are distinct from classical ILs
- IL-20: biological functions mediated through two types of receptor complexes.
- Immunopathogenesis of psoriasis
- The expanded family of class II cytokines that share the IL‐10 receptor‐2 (IL‐10R2) chain
- Interleukin‐20 as a Target in Psoriasis Treatment
- Three decades of psoriasis research: where has it led us?
- The Therapeutic Potential of Anti-Interleukin-20 Monoclonal Antibody
- Ultraviolet B Light Stimulates Interleukin-20 Expression by Human Epithelial Keratinocytes
- Interleukin‐20 plays a critical role in maintenance and development of psoriasis in the human xenograft transplantation model
- Interleukin-20 promotes angiogenesis in a direct and indirect manner
- IL-10 family of cytokines.
- IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression.
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