Cutting Edge: IL-26 Signals through a Novel Receptor Complex Composed of IL-20 Receptor 1 and IL-10 Receptor 2 1
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Summary
It is demonstrated that the active receptor complex for IL-26 is a heterodimer composed of two receptor proteins: IL-20R1 and IL-10R2, demonstrating that this receptor combination is unique and specific forIL-26.
- Type
- article
- Published
- 2004-02-15
- Cited by
- 176
- References
- 23
- Access
- Open access
- OpenAlex
- https://openalex.org/W1788079032
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1047807
Keywords
Receptor, Interleukin-21 receptor, Biology, Cell biology, Interleukin-4 receptor
References
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- Class II cytokine receptors and their ligands: Key antiviral and inflammatory modulators
- Identification and functional characterization of a second chain of the interleukin‐10 receptor complex
- Induction of a Novel Cellular Homolog of Interleukin-10, AK155, by Transformation of T Lymphocytes with Herpesvirus Saimiri
- Interleukin 24 (MDA-7/MOB-5) Signals through Two Heterodimeric Receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2*
- Cloning, expression and initial characterisation of interleukin-19 (IL-19), a novel homologue of human interleukin-10 (IL-10)
- The family of IL-10-related cytokines and their receptors: related, but to what extent?
- A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist
- Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
- Characterization of the recombinant extracellular domains of human interleukin-20 receptors and their complexes with interleukin-19 and interleukin-20.
- Cutting Edge: STAT Activation By IL-19, IL-20 and mda-7 Through IL-20 Receptor Complexes of Two Types1
- Cutting Edge: Immune Cells as Sources and Targets of the IL-10 Family Members?
- Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20.
- Interleukin (IL)-22, a Novel Human Cytokine That Signals through the Interferon Receptor-related Proteins CRF2–4 and IL-22R*
Cited by
- Cytokine induction of interleukin‐24 in human peripheral blood mononuclear cells
- Type III IFN Receptor Expression and Functional Characterisation in the Pteropid Bat, Pteropus alecto
- Lineage-specific adjacent IFNG and IL26 genes share a common distal enhancer element
- Identification of interleukin-26 in the dromedary camel (Camelus dromedarius): Evidence of alternative splicing and isolation of novel splice variants
- Role of IL-22 in microbial host defense.
- The Molecular Basis of IL-10 Function: From Receptor Structure to the Onset of Signaling
- Interleukin-10 in Health and Disease
- Microarray analysis of differentially regulated genes in human leukemia cells after expression of the inositol 5-phosphatase SHIP
- The Effects of IL-20 Subfamily Cytokines on Reconstituted Human Epidermis Suggest Potential Roles in Cutaneous Innate Defense and Pathogenic Adaptive Immunity in Psoriasis
- Structural studies of the interleukin-19 subfamily of cytokines.
- The role of the IL23/IL17 pathway in inflammatory bowel disease
- Interleukins and STAT signaling.
- Targeting Th17 Effector Cytokines for the Treatment of Autoimmune Diseases
- TH17 cells promote microbial killing and innate immune sensing of DNA via interleukin 26
- Interleukin-26: An Emerging Player in Host Defense and Inflammation
- Interleukin-22 and its crystal structure.
- The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.
- IL-26 Promotes the Proliferation and Survival of Human Gastric Cancer Cells by Regulating the Balance of STAT1 and STAT3 Activation
- STAT1 and pathogens, not a friendly relationship
- Interferon-Lambda: A New Addition to an Old Family
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