Brief report: Killer cell defect and persistent immunological abnormalities in two patients with chronic active epstein‐barr virus infection
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Summary
The father, who suffered from the syndrome for more than 15 years, lacked (or lost) antibodies to EBV‐envelope and infected cell membranes, such as antibody‐dependent cellular cytotoxicity (ADCC), neutralizing (NT), and gp 350/220 antibodies.
- Type
- article
- Published
- 1989-06-01
- Cited by
- 67
- References
- 33
- OpenAlex
- https://openalex.org/W2002052039
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9026874
Keywords
Antibody-dependent cell-mediated cytotoxicity, Virology, Antibody, Immunology, Antigen
References
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- A familial syndrome of susceptibility to chronic active Epstein-Barr virus infection.
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- A nonstructural polypeptide encoded by immediate-early transcription unit 1 of murine cytomegalovirus is recognized by cytolytic T lymphocytes
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- Successful treatment of chronic active Epstein-Barr virus infection with recombinant interleukin-2.
- Chronic active Epstein-Barr virus infection
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- Lytic, nontransforming Epstein-Barr virus (EBV) from a patient with chronic active EBV infection.
- Chronic Epstein-Barr virus infection associated with fever and interstitial pneumonitis. Clinical and serologic features and response to antiviral chemotherapy.
Cited by
- Interleukin-15 as an activator of natural killer cell-mediated antiviral response.
- Human natural killer cell activation and differentiation in health and viral infection
- T-helper cell immunity against human parvovirus B19
- T Cells in Patients with B-cell Chronic Lymphocytic Leukemia (B-CLL) and Multiple Myeloma (MM) An Immunological Study
- Implications for Gene Therapy-Limiting Expression of IL-2Rγc Delineate Differences in Signaling Thresholds Required for Lymphocyte Development and Maintenance
- Epstein-Barr viral gene expression in B-lymphocytes.
- Expression and function of the small immune adaptor protein SAP
- Etude des populations lymphocytaires exprimant des récepteurs spécifiques de molécules HLA de classe I au cours de l'hépatite virale C chronique
- Dendritic Cells Mediate NK Cell Help for Th1 and CTL Responses: Two-Signal Requirement for the Induction of NK Cell Helper Function 1
- Autoimmunity in human primary immunodeficiency diseases.
- Chronic active Epstein-Barr virus infection associated with mutations in perforin that impair its maturation.
- Epstein–barr virus‐associated primary b‐cell lymphoproliferative disorder of the cerebellum in an immune competent man
- Development and functions of natural killer cells
- SH2D1A and slam protein expression in human lymphocytes and derived cell lines
- Interleukin 17 modulates the immune response to vaccinia virus infection.
- HIV-1 Vpr Triggers Natural Killer Cell–Mediated Lysis of Infected Cells through Activation of the ATR-Mediated DNA Damage Response
- Human NK cells can control CMV infection in the absence of T cells.
- Radioimmunoprecipitation in the diagnosis of chronic active epstein‐barr virus infection
- Chronic, active Epstein-Barr virus infection
- Consensual immunity: success-driven development of T-helper-1 and T-helper-2 responses
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