Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

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Summary

Systemic lupus erythematosus is a multisystem autoimmune disease in which the autoantibody response targets a variety of autoantigens of diverse subcellular location, and it is shown that they are clustered in two distinct populations of blebs at the surface of apoptotic cells.

Type
article
Published
1994-04-01
Cited by
1,831
References
77
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Open access

Keywords

Ribonucleoprotein, Autoantibody, Heterogeneous nuclear ribonucleoprotein, Endoplasmic reticulum, Biology

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