Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

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Summary

It is found that pancreatic cancers contain an average of 63 genetic alterations, the majority of which are point mutations, which defined a core set of 12 cellular signaling pathways and processes that were each genetically altered in 67 to 100% of the tumors.

Type
article
Published
2008-09-04
Cited by
4,034
References
42
Access
Open access

Keywords

Biology, Carcinogenesis, Pancreatic cancer, Transcriptome, Gene

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