Metagenomic biomarker discovery and explanation
Explore this paper's citation graph
Summary
A new method for metagenomic biomarker discovery is described and validates by way of class comparison, tests of biological consistency and effect size estimation to address the challenge of finding organisms, genes, or pathways that consistently explain the differences between two or more microbial communities.
- Type
- article
- Published
- 2011-06-24
- Cited by
- 14,286
- References
- 124
- Access
- Open access
- OpenAlex
- https://openalex.org/W2133856765
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2099459
Keywords
Metagenomics, Biology, Computational biology, Human genetics, Genome Biology
References
- Incorporating prior knowledge to facilitate discoveries in a genome-wide association study on age-related macular degeneration
- Multivariate Cutoff Level Analysis (MultiCoLA) of large community data sets
- Ecology: The Experimental Analysis of Distribution and Abundance
- Modern Applied Statistics with S
- Host specificity in marine sponge-associated bacteria, and potential implications for marine microbial diversity.
- Research
- Galaxy, a web-based genome analysis tool for experimentalists
- Changes in the Composition of the Human Fecal Microbiome After Bacteriotherapy for Recurrent Clostridium difficile-associated Diarrhea
- Specified Species in Gingival Crevicular Fluid Predict Bacterial Diversity
- On a Test of Whether one of Two Random Variables is Stochastically Larger than the Other
- The properties of high-dimensional data spaces: implications for exploring gene and protein expression data
- Bacterial Community Variation in Human Body Habitats Across Space and Time
- A genomic perspective on protein families.
- Statistical Methods for Detecting Differentially Abundant Features in Clinical Metagenomic Samples
- Metagenomics: Facts and Artifacts, and Computational Challenges*
- Some distance properties of latent root and vector methods used in multivariate analysis
- Survival of Campylobacter jejuni under Conditions of Atmospheric Oxygen Tension with the Support of Pseudomonas spp
- THE USE OF MULTIPLE MEASUREMENTS IN TAXONOMIC PROBLEMS
- A Primer on Metagenomics
- Matplotlib: A 2D Graphics Environment
Cited by
- Characterizing the Role of the Gut Microbiome in Colorectal Cancer.
- Exploiting gut bacteriophages for human health.
- Vertically transmitted fecal IgA levels distinguish extra-chromosomal phenotypic variation
- Complementary seminovaginal microbiome in couples.
- Marked seasonal variation in the wild mouse gut microbiota
- The BBaRTS Healthy Teeth Behaviour Change Programme for preventing dental caries in primary school children: study protocol for a cluster randomised controlled trial
- Mucosa-attached bacterial community in Crohn's disease coheres with the clinical disease activity index.
- Environment and host species shape the skin microbiome of captive neotropical bats
- Microbial Community Patterns Associated with Automated Teller Machine Keypads in New York City
- VirusSeeker, a computational pipeline for virus discovery and virome composition analysis
- Changes in land use driven by urbanization impact nitrogen cycling and the microbial community composition in soils
- Mucosal microbiome dysbiosis in gastric carcinogenesis
- Microbial Disruption Indices to Detect Colonization With Multidrug-Resistant Organisms
- Feed additives shift gut microbiota and enrich antibiotic resistance in swine gut.
- Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice
- Influenza A virus subtype H9N2 infection disrupts the composition of intestinal microbiota of chickens.
- Differentially Regulated Host Proteins Associated with Chronic Rhinosinusitis Are Correlated with the Sinonasal Microbiome
- Isolation in small populations of Wayampi Amerindians promotes endemicity and homogenisation of their faecal virome, but its distribution is not entirely random
- The influence of microbial communities for triadimefon enantiomerization in soils with different pH values.
- 16S rRNA gene sequencing reveals altered composition of gut microbiota in individuals with kidney stones
Related papers
- FOXM1 binds directly to non-consensus sequences in the human genome
- The many uses of a genome sequence
- Comparative genomics of Drosophila and human core promoters
- Q & A: the Snyderome
- When (distant) relatives stay too long: implications for cancer medicine
- Out of Africa
- Single Cell Genomics meeting in Stockholm: from single cells to cell types
- Next-generation human genetics