Permeation prediction of M100240 using the parallel artificial membrane permeability assay.

Keywords

Permeation, Chemistry, Chromatography, Membrane, Synthetic membrane

References

• Pharmacoscintigraphic Assessment of the Regional Drug Absorption of the Dual Angiotensin‐Converting Enzyme/Neutral Endopeptidase Inhibitor, M100240, in Healthy VolunteersNancy Martin, Kathryn R. Collison, Louis L. Martin — 2003
• A comparative study of artificial membrane permeability assay for high throughput profiling of drug absorption potential.Chengyue Zhu, Lan Jiang, Teng‐Man Chen — 2002
• Physicochemical high throughput screening: parallel artificial membrane permeation assay in the description of passive absorption processes.Manfred Kansy, Frank Senner, Klaus Gubernator — 1998
• High Throughput Prediction of Oral Absorption: Improvement of the Composition of the Lipid Solution Used in Parallel Artificial Membrane Permeation AssayKiyohiko Sugano, Hirokazu Hamada, Minoru Machida — 2001
• Graphical model for estimating oral bioavailability of drugs in humans and other species from their Caco-2 permeability and in vitro liver enzyme metabolic stability rates.Arun K. Mandagere, Thomas N. Thompson, Kin‐Kai Hwang — 2002
• High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.Frank Wohnsland, Bernard Faller — 2001
• Assessing the absorption of new pharmaceuticals.Ismael J. Hidalgo — 2001
• Pharmaceutical innovation by the seven UK-owned pharmaceutical companies (1964-1985).RA Prentis, Y. Lis, SR Walker — 1988
• Managing the drug discovery/development interfaceTony Kennedy — 1997
• Site-specific absorption of M100240 and MDL 100,173 in rats evaluated using Sweetana-Grass diffusion chamber technology.Kin‐Kai Hwang, Lan Jiang, Ying Ren — 2002
• Characterization of a dual inhibitor of angiotensin I-converting enzyme and neutral endopeptidase.John F. French, Gary A. Flynn, Eugène L. Giroux — 1994

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• Development and evaluation of an in vitro method for prediction of human drug absorption II. Demonstration of the method suitability.Giovanna Corti, Francesca Maestrelli, Marzia Cirri — 2006
• Evaluation of the permeability and P‐glycoprotein efflux of carbamazepine and several derivatives across mouse small intestine by the Ussing chamber techniqueAna Fortuna, Gilberto Alves, Amílcar Falcão — 2012
• Quantification and characterization of P-glycoprotein-substrate interactions.Ewa Gatlik-Landwojtowicz, Päivi Äänismaa, Anna Seelig — 2006
• Engineering and validation of a novel lipid thin film for biomembrane modeling in lipophilicity determination of drugs and xenobioticsSunday Olakunle Idowu, Morenikeji Adeyemo, Udochi Ogbonna — 2009
• Comparison of Drug Permeabilities and BCS Classification: Three Lipid-Component PAMPA System Method versus Caco-2 MonolayersZeynep Şafak Teksin, Paul Seo, James E. Polli — 2010
• Physicochemical characterization and toxicity of decursin and their derivatives from Angelica gigas.Bimit Mahat, Jung‐woo Chae, In‐hwan Baek — 2012
• On-resin N-methylation of cyclic peptides for discovery of orally bioavailable scaffoldsTina R. White, Chad M. Renzelman, Arthur C Rand — 2011
• Lipid composition effect on permeability across PAMPA.Paul Seo, Zeynep Şafak Teksin, Joseph P. Y. Kao — 2006
• The utility of rat jejunal permeability for biopharmaceutics classification systemParvin Zakeri‐Milani, Hadi Valizadeh, Hosnieh Tajerzadeh — 2009
• Advances in screening for membrane permeability: high-resolution PAMPA for medicinal chemists.Manfred Kansy, Alex Avdeef, Holger Fischer — 2004
• The rise of PAMPAAlex Avdeef — 2005
• Physiologically based pharmacokinetic models: integration of in silico approaches with micro cell culture analogues.A. Chen, Martin L. Yarmush, Timothy J. Maguire — 2012
• Development and evaluation of an in vitro method for prediction of human drug absorption I. Assessment of artificial membrane composition.Giovanna Corti, Francesca Maestrelli, Marzia Cirri — 2006
• Crystal-liquid Fugacity Ratio as a Surrogate Parameter for Intestinal Permeability.Parvin Zakeri‐Milani, Zohreh Fasihi, Jafar Âkbari — 2016
• The effect of silver nanoparticles on the penetration properties of the skin and quantification of their permeation through skin barrierAdéla Jeništová, Martin Loula, Oto Mestek — 2020
• Application of Physicochemical Data to Support Lead Optimization by Discovery TeamsL. Di, E. Kerns — 2006

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