Preoperative versus postoperative chemoradiotherapy for locally advanced rectal cancer: results of the German CAO/ARO/AIO-94 randomized phase III trial after a median follow-up of 11 years.
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Summary
There is a persisting significant improvement of pre- versus postoperative CRT on local control; however, there was no effect on overall survival.
- Type
- article
- Published
- 2012-04-23
- Cited by
- 1,896
- References
- 22
- Access
- Open access
- OpenAlex
- https://openalex.org/W2123377696
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8506908
Keywords
Medicine, Colorectal cancer, Total mesorectal excision, Cumulative incidence, Surgery
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Cited by
- Current perspectives on preoperative integrated treatments for locally advanced rectal cancer: a review of agreement and controversies.
- Wait-and-see-Strategie bei klinischem vollständigem Ansprechen nach Radiochemotherapie bei Rektumkarzinomen
- Future directions in combined modality therapy for rectal cancer: reevaluating the role of total mesorectal excision after chemoradiotherapy
- Neoadjuvant chemotherapy and primary‐first approach for rectal cancer with synchronous liver metastases
- Current treatment of rectal cancer adapted to the individual patient.
- A hundred patients with vertical rectus abdominis myocutaneous (VRAM) flap for pelvic reconstruction after total pelvic exenteration
- Early and late toxicity of radiotherapy for rectal cancer.
- Adjuvant chemotherapy for rectal cancer patients treated with preoperative (chemo)radiotherapy and total mesorectal excision: a Dutch Colorectal Cancer Group (DCCG) randomized phase III trial.
- Pathologisches Staging und Response-Evaluation beim Rektumkarzinom
- Molecular Predictors of Response to Neoadjuvant Chemoradiation for Rectal Cancer
- Preoperative long-course chemoradiotherapy plus adjuvant chemotherapy versus short-course radiotherapy without adjuvant chemotherapy both with delayed surgery for stage II-III resectable rectal cancer: 5-Year survival data of a randomized controlled trial.
- Addition of oxaliplatin to capecitabine-based preoperative chemoradiotherapy for locally advanced rectal cancer: Long-term outcome of a phase II study
- Impact of age on the efficacy of oxaliplatin in the preoperative chemoradiotherapy and adjuvant chemotherapy of rectal cancer: a post hoc analysis of the CAO/ARO/AIO-04 phase III trial
- Perfusion-sensitive parameters of intravoxel incoherent motion MRI in rectal cancer: evaluation of reproducibility and correlation with dynamic contrast-enhanced MRI
- Prognostic Implication of Negative Lymph Node Count in ypN+ Rectal Cancer after Neoadjuvant Chemoradiotherapy and Construction of a Prediction Nomogram
- Comment on the editorial of Sautter-Bihl et al. in Strahlentherapie und Onkologie 2013 189:105–110
- Improved survival in rectal cancer patients who are treated with long‐course versus short‐course neoadjuvant radiotherapy: A propensity‐matched analysis of the NCDB
- Postoperative XELOX therapy for patients with curatively resected high-risk stage II and stage III rectal cancer without preoperative chemoradiation: a prospective, multicenter, open-label, single-arm phase II study
- Rektumkarzinom – Besondere Aspekte der Pathologie
- T4 rectal cancer: do we always need an exenteration?
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