Developmental pharmacology--drug disposition, action, and therapy in infants and children.
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Summary
This review examines the developmental changes that profoundly affect the responses of children to medications and related therapies in the very young.
- Type
- review
- Published
- 2003-09-18
- Cited by
- 2,225
- References
- 101
- OpenAlex
- https://openalex.org/W2122527560
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:46013486
Keywords
Medicine, Clinical pharmacology, Affect (linguistics), Disposition, Drug
References
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- Age dependence of erythromycin rectal bioavailability in children.
- Roles of cytochrome P4502C9 and cytochrome P4502C19 in the stereoselective metabolism of phenytoin to its major metabolite.
- Surface electrical capacitance as a noninvasive bedside measure of epidermal barrier maturation in the newborn infant.
- Relative bioavailability and plasma paracetamol profiles of Panadol® suppositories in children
- Developmental expression of CYP2E1 in the human liver. Hypermethylation control of gene expression during the neonatal period.
- Pediatric Dosage Handbook
- Clinical Trials in Children
- Gastric retention in neonates.
- Digoxin inactivation by the gut flora in infancy and childhood.
- Handbook of basic pharmacokinetics-- including clinical applications
- Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation.
- Handbook of basic pharmacokinetics
- P-450 HFLa, a form of cytochrome P-450 purified from human fetal livers, is the 16 alpha-hydroxylase of dehydroepiandrosterone 3-sulfate.
- Liver volume as a determinant of drug clearance in children and adolescents.
- Identification of the human hepatic cytochromes P450 involved in the in vitro oxidation of antipyrine.
Cited by
- Neonatal clinical pharmacology: recent observations of relevance for anaesthesiologists.
- Safety of Medication in Paediatrics
- Both postnatal and postmenstrual age contribute to the interindividual variability in tramadol glucuronidation in neonates.
- Pediatric HIV infection: the state of antiretroviral therapy
- Children Are Not Just Small Adults: The Urgent Need for High-Quality Trial Evidence in Children
- Population approaches in paediatrics
- Evidence for Clinical Safety, Efficacy, and Parent and Physician Perceptions of Levocetirizine for the Treatment of Children with Allergic Disease
- Basics and dynamics of neonatal and pediatric pharmacology.
- A cautionary tale: dosing chemotherapy in infants with retinoblastoma.
- Adverse drug reaction-related admissions in paediatrics, a prospective single-centre study
- Pharmacokinetic Profile of Artemisinin Derivatives and Companion Drugs Used in Artemisinin-Based Combination Therapies for the Treatment of Plasmodium falciparum Malaria in Children
- Safety of Medical Interventions in Children Versus Adults
- Extemporaneously Compounded Oral Medicines in European Hospital Pharmacies
- Dosage individualization in children: integration of pharmacometrics in clinical practice
- Pharmacogenomics in children.
- Optimal design in pediatric pharmacokinetic and pharmacodynamic clinical studies
- Systemic exposure to menthol following administration of peppermint oil to paediatric patients
- Preterm Versus Term Children: Analysis of Sedation/Anesthesia Adverse Events and Longitudinal Risk
- Efficacy of Six-Week Extended-Dose Nevirapine Varies by Infant Birth Weight with Greatest Relative Efficacy in Low Birth Weight Infants
- Congenital Infantile Fibrosarcoma in the Premature Infant
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