Prospects for inferring very large phylogenies by using the neighbor-joining method.

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Summary

The simulation results show that the accuracy of NJ trees decline only by approximately 5% when the number of sequences used increases from 32 to 4,096 (128 times) even in the presence of extensive variation in the evolutionary rate among lineages or significant biases in the nucleotide composition and transition/transversion ratio.

Type
article
Published
2004-07-27
Cited by
5,607
References
41
Access
Open access

Keywords

Tree (set theory), Transversion, Pairwise comparison, Substitution (logic), Inference

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