Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.
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Summary
The GAL4 system, a system for targeted gene expression that allows the selective activation of any cloned gene in a wide variety of tissue- and cell-specific patterns, has been designed and used to expand the domain of embryonic expression of the homeobox protein even-skipped.
- Type
- article
- Published
- 1993-06-01
- Cited by
- 9,924
- References
- 75
- OpenAlex
- https://openalex.org/W2110643873
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:8536961
Keywords
Biology, Enhancer, Phenotype, Gene, Transcription factor
References
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- Redesigning the body plan of Drosophilaby ectopic expression of the homoeotic gene Antennapedia
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- Characterization of putative regulators of the small GTPase, Rac, in Drosophila
- A PI3K-mediated negative feedback regulates Drosophila motor neuron excitability
- Chemical communication in insects: the peripheral odour coding system of Drosophila melanogaster.
- Lethal of scute, a proneural gene, participates in the specification of muscle progenitors during Drosophila embryogenesis.
- trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila.
- Direct and long-range action of a DPP morphogen gradient.
- Functional and regulatory interactions between Hox and extradenticle genes.
- Nuclear access and action of notch in vivo.
- Cell determination and transdetermination in Drosophila imaginal discs.
- Mosaic analysis with a repressible cell marker for studies of gene function in neuronal morphogenesis.
- Paraoxonase 1, quorum sensing, and P. aeruginosa infection: a novel model.
- LOLA has the properties of a master regulator of axon-target interaction for SNb motor axons of Drosophila.
- Chip and apterous physically interact to form a functional complex during Drosophila development.
- The Neuron-Enriched Splicing Pattern ofDrosophila erect wing Is Dependent on the Presence of ELAV Protein
- Transgenic organisms in evolutionary ecology.
- Genetic control of epithelial cell polarity: Lessons from Drosophila
- The Ste20 Kinase Misshapen Regulates Both Photoreceptor Axon Targeting and Dorsal Closure, Acting Downstream of Distinct Signals
- The AP-2 transcription factor is required for joint formation and cell survival in Drosophila leg development.
- Tauopathy in Drosophila: Neurodegeneration Without Neurofibrillary Tangles
- Regulating axon branch stability: the role of p190 RhoGAP in repressing a retraction signaling pathway.
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