Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs.
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Summary
Together, these data show that human pri-miRNAs are not only structurally similar to mRNAs but can, in fact, function both as pri- miRNAs and m RNAs.
- Type
- article
- Published
- 2004-12-01
- Cited by
- 2,002
- References
- 35
- Access
- Open access
- OpenAlex
- https://openalex.org/W2106929712
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:39386865
Keywords
Biology, microRNA, Polyadenylation, Untranslated region, Primary transcript
References
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- MicroRNAs Modulate Hematopoietic Lineage Differentiation
- Self-assembly of mesoscopically ordered chromatic polydiacetylene/silica nanocomposites
- Identification of Virus-Encoded MicroRNAs
Cited by
- Enhancing CHO cell productivity through the stable depletion of microRNA-23
- RARs and microRNAs.
- Contingent microARN des exosomes, diagnostic et physiopathologie des gliomes
- Peroxisome Proliferator-Activated Receptor α Regulates a MicroRNA-Mediated Signaling Cascade Responsible for Hepatocellular Proliferation
- A microRNA DNA methylation signature for human cancer metastasis
- miRNA expression profiling in melanocytes and melanoma cell lines reveals miRNAs associated with formation and progression of malignant melanoma.
- C19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts
- Identification of Nutrient-Responsive Arabidopsis and Rapeseed MicroRNAs by Comprehensive Real-Time Polymerase Chain Reaction Profiling and Small RNA Sequencing1[C][W][OA]
- Current knowledge of MicroRNAs and noncoding RNAs in virus-infected cells.
- MicroRNA‐29a regulates pro‐inflammatory cytokine secretion and scavenger receptor expression by targeting LPL in oxLDL‐stimulated dendritic cells
- Stars and Symbiosis: MicroRNA- and MicroRNA*-Mediated Transcript Cleavage Involved in Arbuscular Mycorrhizal Symbiosis1[W][OA]
- Functional, structural, and sequence studies of microRNA.
- microRNA Biogenesis and Function : An overview.
- Implication of microRNAs in the Pathogenesis of MDS
- Regulatory RNAs in mammals.
- Modulation of immune responses following solid organ transplantation by microRNA
- Identification and analysis of the proximal promoters of microRNA genes in Arabidopsis.
- Long Noncoding RNAs-Related Diseases, Cancers, and Drugs
- An RNAi-Based Approach to Down-Regulate a Gene Family In Vivo
- MicroRNAs in Cervical Cancer: Evidences for a miRNA Profile Deregulated by HPV and Its Impact on Radio-Resistance
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