Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
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- Type
- article
- Published
- 2008-02-20
- Cited by
- 1,831
- References
- 48
- OpenAlex
- https://openalex.org/W2106219965
Keywords
Proinsulin, Enteroendocrine cell, Endoderm, Endocrinology, Stem cell
References
- Morphology and Function of Cultured Human Fetal Pancreatic Cells Transplanted into Athymic Mice: A Longitudinal Study
- Molecular basis of vertebrate endoderm development.
- Histology for Pathologists
- Histology for Pathologists
- Expression pattern of IAPP and prohormone convertase 1/3 reveals a distinctive set of endocrine cells in the embryonic pancreas.
- Ex vivo analysis of acinar and endocrine cell development in the human embryonic pancreas
- Reversal of diabetes by human fetal pancreas. Optimization of requirements in the hyperglycemic nude mouse.
- REGULATION OF BLOOD GLUCOSE TO HUMAN LEVELS BY HUMAN FETAL PANCREATIC XENOGRAFTS
- Generation of Insulin‐Producing Islet‐Like Clusters from Human Embryonic Stem Cells
- Major species differences between humans and rodents in the susceptibility to pancreatic beta-cell injury.
- Retinoid signaling controls mouse pancreatic exocrine lineage selection through epithelial-mesenchymal interactions.
- Maturation of the response of human fetal pancreatic expiants to glucose
- Identification of β-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA
- Gene regulatory factors in pancreatic development
- Differential sensitivity of GLUT1- and GLUT2-expressing beta cells to streptozotocin.
- Human β Cells Are Exceedingly Resistant to Streptozotocin in Vivo.
- Efficient differentiation of human embryonic stem cells to definitive endoderm
- Regulation of pancreatic endocrine cell differentiation by sulphated proteoglycans
- Inhibition of c-jun N terminal kinase (JNK) improves functional beta cell mass in human islets and leads to AKT and glycogen synthase kinase-3 (GSK-3) phosphorylation
- Production of pancreatic hormone–expressing endocrine cells from human embryonic stem cells
Cited by
- Current research concerning the RAS in pancreatic stem cells.
- Colony-forming progenitor cells in the postnatal mouse liver and pancreas give rise to morphologically distinct insulin-expressing colonies in 3D cultures.
- Challenges and prospects for stem cell-based therapy in diabetes mellitus.
- Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency
- Immune modulation with amniotic epithelial cells in pancreatic islet transplantation
- Regenerative medicine for diabetes: differentiation of human pluripotent stem cells into functional β-cells in vitro and their proposed journey to clinical translation.
- Basic techniques for pancreatic research.
- Small molecules in cellular reprogramming and differentiation.
- The effect of fetal liver-derived cell suspension allotransplantation on patients with diabetes: first year of follow-up.
- The programmable cell of monocytic origin (PCMO): a potential adult stem/progenitor cell source for the generation of islet cells.
- Derivation of insulin-producing beta-cells from human pluripotent stem cells.
- Controlling Cell Density by Micropatterning Regulates Smad Signalling and Mesendoderm Differentiation of Human Embryonic Stem Cells
- Human Serum versus Human Serum Albumin Supplementation in Human Islet Pretransplantation Culture: In Vitro and in Vivo Assessment
- Endothelium-derived essential signals involved in pancreas organogenesis.
- Novel Culture Strategies and Signal Transduction Pathways of Pluripotent Stem Cells
- Bioengineered stem cells as an alternative for islet cell transplantation.
- 多能性幹細胞を用いた 膵 β 細胞分化誘導研究の最新動向
- In vivo and in vitro approaches to induce beta cells from stem and progenitor cells
- Studies of Innate and Adaptive Immunity in Islet Transplantation
- Improvement of Cell Survival During Human Pluripotent Stem Cell Definitive Endoderm Differentiation
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