Current research concerning the RAS in pancreatic stem cells.
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Summary
A lack of availability of human donor islets for transplantation hampers the development and implementation of such novel therapeutic strategies, and the induction of either embryonic or somatic stem cell differentiation into islet cells offers hope.
- Type
- review
- Published
- 2010-01-01
- Cited by
- 1
- References
- 98
- OpenAlex
- https://openalex.org/W388540
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:32047263
Keywords
Stem cell, Context (archaeology), Pancreas, Embryonic stem cell, Transplantation
References
- Islet-Derived Fibroblast-Like Cells Are Not Derived via Epithelial-Mesenchymal Transition From Pdx-1 or Insulin-Positive Cells
- Epithelial cells within the human pancreas do not coexpress mesenchymal antigens: epithelial–mesenchymal transition is an artifact of cell culture
- Early expression of all the components of the renin-angiotensin-system in human development.
- PDZ-Domain Containing-2 (PDZD2) Drives the Maturity of Human Fetal Pancreatic Progenitor-Derived Islet-Like Cell Clusters With Functional Responsiveness Against Membrane Depolarization
- Reprogramming of pancreatic beta cells into induced pluripotent stem cells.
- Congenital anomalies of the kidney and urinary tract--role of the loss of function mutation in the pluripotent angiotensin type 2 receptor gene.
- Mesenchymal Stem Cells Adopt &bgr;-Cell Fate Upon Diabetic Pancreatic Microenvironment
- In vivo treatment with glucagon-like peptide 1 promotes the graft function of fetal islet-like cell clusters in transplanted mice.
- In vitro derivation of functional insulin-producing cells from human embryonic stem cells
- Growth and regeneration of adult beta cells does not involve specialized progenitors.
- Directed differentiation of human embryonic stem cells towards a pancreatic cell fate
- Role of the renin-angiotensin system in primitive erythropoiesis in the chick embryo.
- Severe ROP in twins after blockage of the renin‐angiotensin system during gestation
- Generation of Insulin‐Producing Islet‐Like Clusters from Human Embryonic Stem Cells
- PDZ-domain containing-2 (PDZD2) is a novel factor that affects the growth and differentiation of human fetal pancreatic progenitor cells.
- Mesenchymal stem cell therapy for diabetes through paracrine mechanisms.
- Synergistic effect of high glucose and ANG II on proliferation of mouse embryonic stem cells: Involvement of PKC and MAPKs as well as AT1 receptor
- Long-Term Correction of Hyperglycemia in Diabetic Mice After Implantation of Cultured Human Cells Derived From Fetal Pancreas
- Fetopathy associated with exposure to angiotensin converting enzyme inhibitors and angiotensin receptor antagonists.
- Endothelial Progenitor Cell Differentiation and Senescence in an Angiotensin II-Infusion Rat Model
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