Modulation of neuronal excitability by intracellular calcium buffering: from spiking to bursting.

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Summary

Theoretical results show that a high calcium buffer concentration alters the characteristic regular firing of cerebellar granule cells and that a transition to various modes of oscillations occurs, including bursting, and suggest that cytosolic calcium buffering capacity can tightly modulate neuronal firing patterns leading to generation of complex patterns.

Type
article
Published
2006-05-01
Cited by
52
References
63

Keywords

Bursting, Calcium, Biophysics, Neuroscience, BAPTA

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