Genomic Signatures of the Haarlem Lineage of Mycobacterium tuberculosis: Implications of Strain Genetic Variation in Drug and Vaccine Development
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Summary
Strain variability such as that described here underscores the need for the definition of a core set of essential genes in M. tuberculosis that are ubiquitously present in all circulating lineages, as a requirement in the development of effective antituberculosis drugs and vaccines.
- Type
- article
- Published
- 2010-07-14
- Cited by
- 22
- References
- 38
- Access
- Open access
- OpenAlex
- https://openalex.org/W2099789145
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:21067756
Keywords
Biology, Mycobacterium tuberculosis, Tuberculosis, Lineage (genetic), Genetics
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Cited by
- Poly-resistant tuberculosis outbreak in Northern Portugal: a nine year tale.
- Prevalence and occurrence rate of Mycobacterium tuberculosis Haarlem family multi-drug resistant in the worldwide population: A systematic review and meta-analysis
- IS-seq: a novel high throughput survey of in vivo IS6110 transposition in multiple Mycobacterium tuberculosis genomes
- Single nucleotide polymorphism (SNP) analysis used for the phylogeny of the Mycobacterium tuberculosis complex based on a pyrosequencing assay
- C-di-GMP signaling and implications for pathogenesis of Mycobacterium tuberculosis
- Vrste, filogenetske karakteristike i genetička osnova rezistencije multirezistentnih sojeva Mycobacterium tuberculosis kompleksa izolovanih u Srbiji
- The universal stress proteins of bacteria
- Prevalence of Beijing and Haarlem genotypes among multidrug-resistant Mycobacterium tuberculosis in Iran: Systematic review and meta-analysis.
- Phylogenetic Analysis of Mycobacterium tuberculosis Strains in Wales by Use of Core Genome Multilocus Sequence Typing To Analyze Whole-Genome Sequencing Data
- Molecular characterization of Mycobacterium tuberculosis isolates from pulmonary tuberculosis patients in Sri Lanka [an abstract of entire text]
- Spatial clustering and genetic diversity of Mycobacterium tuberculosis isolate among pulmonary tuberculosis suspected patients, Arsi Zone, Ethiopia
- Distribution of Mycobacterium tuberculosis lineages in South America
- BCGΔBCG1419c increased memory CD8+ T cell-associated immunogenicity and mitigated pulmonary inflammation compared with BCG in a model of chronic tuberculosis
- Synthesis, Anticancer and Antitubercular Properties of New Chalcones and Their Nitrogen-Containing Five-Membered Heterocyclic Hybrids Bearing Sulfonamide Moiety
- QSAR Studies, Molecular Docking, Molecular Dynamics, Synthesis, and Biological Evaluation of Novel Quinolinone-Based Thiosemicarbazones against Mycobacterium tuberculosis
- A review of the efficacy of clinical tuberculosis vaccine candidates in mouse models
- Potential Role of Whole Genome Sequencing to Predict the Virulence, Anti-TB Resistance, and Variants of Mycobacterium tuberculosis Strains from Rifampicin-sensitive Pulmonary Tuberculosis Patients in Surabaya, East Java, Indonesia.
- Real-time PCR assay for robust detection and global surveillance of the Mycobacterium tuberculosis Haarlem genotype
- Culture-independent detection and characterisation of Mycobacterium tuberculosis and M. africanum in sputum samples using shotgun metagenomics on a benchtop sequencer
- Additional file 2 of Spatial clustering and genetic diversity of Mycobacterium tuberculosis isolate among pulmonary tuberculosis suspected patients, Arsi Zone, Ethiopia
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