A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma
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Summary
The isolation of a complementary DNA segment that detects a chromosomal segment having the properties of the gene at this locus is described, which is expressed in many tumour types, but no RNA transcript has been found in retinoblastomas and osteosarcomas.
- Type
- article
- Published
- 1986-10-16
- Cited by
- 2,927
- References
- 36
- Access
- Open access
- OpenAlex
- https://openalex.org/W2099742439
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4326367
Keywords
Locus (genetics), Retinoblastoma, Biology, Genetics, Gene
References
- Accuracy of detection of the retinoblastoma gene by esterase D linkage.
- Anti-oncogenes. A subset of regulatory genes involved in carcinogenesis?
- Molecular cloning of lethal(2)giant larvae, a recessive oncogene of Drosophila melanogaster.
- Second nonocular tumors in retinoblastoma survivors. Are they radiation-induced?
- Adenovirus E1A‐mediated regulation of class I MHC expression.
- Chromosome 13 homozygosity in osteosarcoma without retinoblastoma.
- Characterization of a new continuous cell line derived from a human retinoblastoma.
- Loss of heterozygosity in three embryonal tumours suggests a common pathogenetic mechanism
- Loss of alleles at polymorphic loci on chromosome 2 in uveal melanoma.
- Gene for hereditary retinoblastoma assigned to human chromosome 13 by linkage to esterase D.
- Expression of recessive alleles by chromosomal mechanisms in retinoblastoma
- Isolation of human chromosome 13-specific DNA sequences cloned from flow sorted chromosomes and potentially linked to the retinoblastoma locus.
- Somatic inactivation of genes on chromosome 13 is a common event in retinoblastoma
- Homozygosity of chromosome 13 in retinoblastoma.
- Loss of genes on the short arm of chromosome 11 in bladder cancer
- Cellular oncogenes and multistep carcinogenesis.
- Cytogenetic analysis of retinoblastoma: evidence for multifocal origin and in vivo gene amplification.
- A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity.
- Analysis of deletions in DNA from patients with Becker and Duchenne muscular dystrophy
- Retinoblastoma: clues to human oncogenesis.
Cited by
- Tumor suppressor genes.
- Loss of allelic heterozygosity on distal chromosome 1p in Merkel cell carcinoma. A marker of neural crest origins?
- The genetics of retinoblastoma.
- Molecular oncogenetics of metastasis.
- Hyperphosphorylation of the retinoblastoma gene product is determined by domains outside the simian virus 40 large-T-antigen-binding regions
- Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells
- How fixed is the differentiated state? Lessons from heterokaryons.
- Absence of TGF-beta receptors and growth inhibitory responses in retinoblastoma cells.
- Recessive genetic deregulation abrogates c-myc suppression by interferon and is implicated in oncogenesis
- Gene for von Recklinghausen neurofibromatosis is in the pericentromeric region of chromosome 17.
- Molecular genetic characterization of CNS tumor oncogenesis.
- Disease diagnosis by recombinant DNA methods.
- Late effects of early childhood cancer therapy.
- Inactivation of the retinoblastoma gene in human lymphoid neoplasms.
- Neuronal and glial properties of a murine transgenic retinoblastoma model.
- Molecular biological aspects of soft tissue tumors.
- Pathological diagnosis of osteosarcoma: the validity of the subclassification and some new diagnostic approaches using immunohistochemistry.
- Enzyme deficiency and tumor suppressor genes: absence of 5'-deoxy-5'-methylthioadenosine phosphorylase in human tumors.
- Total loss of p53 DNA sequences in acute myeloid leukemia.
- Human TRE17 Oncogene Is Generated from a Family of Homologous Polymorphic Sequences by Single-Base Changes
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