Enhancer-PRE communication contributes to the expansion of gene expression domains in proliferating primordia
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Summary
Expiration of hedgehog in the posterior compartment of the Drosophila wing results from the communication between a previously defined ME and a nearby cis-regulatory element termed the C enhancer, suggesting that enhancers and MEs of different genes are interchangeable modules whose communication is involved in restricting and expanding the domains of gene expression.
- Type
- article
- Published
- 2011-08-01
- Cited by
- 30
- References
- 56
- Access
- Open access
- OpenAlex
- https://openalex.org/W2099614444
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10027782
Keywords
Enhancer, Biology, Enhancer trap, Regulation of gene expression, Hedgehog
References
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- Dorsal-ventral signaling in limb development.
- Transcription Factor Map Alignment of Promoter Regions
- Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene
Cited by
- Gene-Regulatory Logic to Induce and Maintain a Developmental Compartment
- The quest for mammalian Polycomb response elements: are we there yet?
- A strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element
- Patterning and growth control by membrane-tethered Wingless
- Modulating and measuring Wingless signalling.
- What are memories made of? How Polycomb and Trithorax proteins mediate epigenetic memory
- Quantitative in vivo analysis of chromatin binding of Polycomb and Trithorax group proteins reveals retention of ASH1 on mitotic chromatin
- Establishment of a Developmental Compartment Requires Interactions between Three Synergistic Cis-regulatory Modules
- Trithorax and Polycomb group-dependent regulation: a tale of opposing activities
- The interplay between morphogens and tissue growth
- Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs
- Genomic dimensions of Su(H)-targeted regulatory belts in Drosophila
- Control of the gene activity by polycomb and trithorax group proteins in Drosophila
- Drosophila DNA-Binding Proteins in Polycomb Repression
- A dynamic cell recruitment process drives growth of the Drosophila wing by overscaling the Vestigial expression pattern
- Robust Wnt signaling is maintained by a Wg protein gradient and Fz2 receptor activity in the developing Drosophila wing
- Inducing your neighbors to become like you: Cell recruitment and its contribution to developmental patterning and growth.
- A theoretical model of Polycomb/Trithorax action unites stable epigenetic memory and dynamic regulation
- Hedgehog signaling and Tre1 regulate actin dynamics through PI(4,5)P2 to direct migration of Drosophila embryonic germ cells
- Cell Recruitment Drives Growth of the Drosophila Wing by Overscaling the Vestigial Expression Pattern
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