Regulation of Ubx Expression by Epigenetic Enhancer Silencing in Response to Ubx Levels and Genetic Variation
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Summary
It is found that large, transient increases in Ubx levels are capable of silencing all enhancer input into Ubx transcription, resulting in the complete silencing of this gene.
- Type
- article
- Published
- 2009-09-01
- Cited by
- 20
- References
- 31
- Access
- Open access
- OpenAlex
- https://openalex.org/W19730678
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:9915349
Keywords
Political science
References
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Cited by
- Eco-evo-devo: the time has come.
- Phenotypic robustness conferred by apparently redundant transcriptional enhancers
- The Hox genes and their roles in oncogenesis
- Segregating Variation in the Polycomb Group Gene cramped Alters the Effect of Temperature on Multiple Traits
- Hox Gene Expression Leads to Differential Hind Leg Development between Honeybee Castes
- The Molecular Basis of Size Differences
- Integration of RNA processing and expression level control modulates the function of the Drosophila Hox gene Ultrabithorax during adult development
- Enhancer-PRE communication contributes to the expansion of gene expression domains in proliferating primordia
- Genome-Wide Tissue-Specific Occupancy of the Hox Protein Ultrabithorax and Hox Cofactor Homothorax in Drosophila
- Insulator elements mediate long-range interactions between polycomb targets and between active enhancers in Drosophila
- Control of Hox transcription factor concentration and cell-to-cell variability by an auto-regulatory switch
- The role of the trithorax group TnaA isoforms in Hox gene expression, and in Drosophila late development
- Low affinity binding sites in an activating CRM mediate negative autoregulation of the Drosophila Hox gene Ultrabithorax
- Dynamics of Gene Co-expression Networks in Time-Series Data: A Case Study in Drosophila melanogaster Embryogenesis
- Hox dosage contributes to flight appendage morphology in Drosophila
- Developmental Robustness: The Haltere Case in Drosophila
- Micromanagement of Drosophila Post-Embryonic Development by Hox Genes
- Visceral organ morphogenesis via calcium-patterned muscle constrictions
- The activity of engrailed imaginal disc enhancers is modulated epigenetically by chromatin and autoregulation
- The activity of engrailed imaginal disc enhancers is modulated epigenetically by chromatin and autoregulation
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