Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice.
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Summary
Results indicate that PD-1 may be an important factor contributing to the prevention of autoimmune diseases and high-titer circulating IgG autoantibodies reactive to a 33-kilodalton protein expressed specifically on the surface of cardiomyocytes.
- Type
- article
- Published
- 2001-01-12
- Cited by
- 1,859
- References
- 14
- OpenAlex
- https://openalex.org/W2098853737
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:36971354
Keywords
Dilated cardiomyopathy, Autoantibody, Heart failure, Cardiomyopathy, Autoimmunity
References
- Recommendations Regarding Quantitation in M-Mode Echocardiography: Results of a Survey of Echocardiographic Measurements
- Demonstration of organ specific antibodies against heart mitochondria (anti-M7) in sera from patients with some forms of heart diseases.
- Report of the 1995 World Health Organization/International Society and Federation of Cardiology Task Force on the Definition and Classification of cardiomyopathies.
- Molecular and immune mechanisms in the pathogenesis of cardiomyopathy--role of viruses, cytokines, and nitric oxide.
- Localization of Rabphilin-3A on the synaptic vesicle.
- T-Independent immune response: new aspects of B cell biology.
- The role of cytoskeletal proteins in cardiomyopathies.
- Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor.
- Complexity in simplicity: monogenic disorders and complex cardiomyopathies.
- Immunological studies on PD-1 deficient mice: implication of PD-1 as a negative regulator for B cell responses.
- Evidence from family studies for autoimmunity in dilated cardiomyopathy.
- Mapping of a functional autoimmune epitope on the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy.
- Antibodies to the ADP/ATP carrier, an autoantigen in myocarditis and dilated cardiomyopathy, penetrate into myocardial cells and disturb energy metabolism in vivo.
- Colocalization of dihydropyridine and ryanodine receptors in neonate rabbit heart using confocal microscopy.
Cited by
- Estudio del rol de la vía de PD-1 sobre la respuesta inmune de células Nk y de los mecanismos inmunológicos inducidos por las células Th9 frente a la infección por M. tuberculosis
- ICOS and CD28: similar or separate costimulators of T cells?
- B7-H1 Is Expressed by Human Endothelial Cells and Suppresses T Cell Cytokine Synthesis1
- Making and breaking tolerance.
- PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells.
- Reviving exhausted T lymphocytes during chronic virus infection by B7-H1 blockade.
- Human corneal endothelial cells expressing programmed death-ligand 1 (PD-L1) suppress PD-1+ T helper 1 cells by a contact-dependent mechanism.
- The mouse resources at the RIKEN BioResource center.
- Costimulatory molecule programmed death-1 in the cytotoxic response during chronic hepatitis C.
- Immunobiology of cancer therapies targeting CD137 and B7-H1/PD-1 cosignal pathways.
- Role of the PD-1 Pathway in the Immune Response
- The role of B cells in animal models of rheumatoid arthritis.
- Programmed death-1/programmed death-L1 signaling pathway and its blockade in hepatitis C virus immunotherapy.
- Molecular Pathways: Targeting CD96 and TIGIT for Cancer Immunotherapy
- PD-1 and its ligands are important immune checkpoints in cancer
- Characterization of the Anti–PD-1 Antibody REGN2810 and Its Antitumor Activity in Human PD-1 Knock-In Mice
- PD-L1 Prevents the Development of Autoimmune Heart Disease in Graft-vs-Host Disease
- Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes
- A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity
- Die Lokalisation von PD-1 während des "Kiss of Death"
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