Reviving exhausted T lymphocytes during chronic virus infection by B7-H1 blockade.
Explore this paper's citation graph
Summary
Blockade of the B7-H1-PD-1 pathway by a monoclonal antibody restored CTL function and reduced viral burden in a chronic-infection mouse model of lymphocytic choriomeningitis virus.
- Type
- article
- Published
- 2006-06-01
- Cited by
- 36
- References
- 16
- OpenAlex
- https://openalex.org/W16650803
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24321429
Keywords
Business, Computer science, Risk analysis (engineering)
References
- The Regulation and Maturation of Antiviral Immune Responses
- B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
- Correlates of immune protection in HIV-1 infection: what we know, what we don't know, what we should know
- Oscillating CD8(+) T cell effector functions after antigen recognition in the liver.
- Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor.
- Immunology of hepatitis B virus and hepatitis C virus infection
- Co-inhibitory molecules of the B7–CD28 family in the control of T-cell immunity
- Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection.
- Restoring function in exhausted CD8 T cells during chronic viral infection
- Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice.
- Compromised virus control and augmented perforin-mediated immunopathology in IFN-gamma-deficient mice infected with lymphocytic choriomeningitis virus.
- Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity.
- Viral Immune Evasion Due to Persistence of Activated T Cells Without Effector Function
- CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
- Molecular Modeling and Functional Mapping of B7-H1 and B7-DC Uncouple Costimulatory Function from PD-1 Interaction
Cited by
- Costimulatory molecule programmed death-1 in the cytotoxic response during chronic hepatitis C.
- Characterization of human IL-35+ regulatory T cells induced by Rhinovirus-treated dendritic cells
- Negative immune checkpoints on T lymphocytes and their relevance to cancer immunotherapy
- Immunotherapy of malignant brain tumors
- How Ebola and Marburg viruses battle the immune system
- Striking Dichotomy of PD‐L1 and PD‐L2 Pathways in Regulating Alloreactive CD4+ and CD8+ T Cells In Vivo
- HLA-restricted CTL that are specific for the immune checkpoint ligand PD-L1 occur with high frequency in cancer patients.
- Peripheral blood gene expression of B7 and CD28 family members associated with tumor progression and microscopic lymphovascular invasion in colon cancer patients
- T-cell dysfunction in HIV-1 infection: targeting the inhibitors
- B7-H1 (PD-L1, CD274) suppresses host immunity in T-cell lymphoproliferative disorders.
- PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: restricted expression of type I interferon receptor by CCR5-expressing leukocytes
- B7-H1 on myeloid-derived suppressor cells in immune suppression by a mouse model of ovarian cancer.
- Human rhinoviruses induce IL‐35‐producing Treg via induction of B7‐H1 (CD274) and sialoadhesin (CD169) on DC
- Inhibitory costimulation and anti-tumor immunity.
- Advances in targeting cell surface signalling molecules for immune modulation
- Lentiviral Vectors Encoding Human Immunodeficiency Virus Type 1 (HIV-1)-Specific T-Cell Receptor Genes Efficiently Convert Peripheral Blood CD8 T Lymphocytes into Cytotoxic T Lymphocytes with Potent In Vitro and In Vivo HIV-1-Specific Inhibitory Activity
- The inhibitory co-receptors: a way to save from anergy the HIV-specific T cells.
- Immunomodulation as an option for the treatment of chronic hepatitis B virus infection: preclinical studies in the woodchuck model
- PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection
- Unexpected Acceleration of Type 1 Diabetes by Transgenic Expression of B7-H1 in NOD Mouse Peri-Islet Glia
Related papers
No related papers recorded.